Coronary/Structural Heart

Windtree Presents Data from its Positive SEISMiC Phase 2 Study of Istaroxime in Early Cardiogenic Shock in a Late-Breaker Presentation at the European Society of Cardiology Heart Failure Meeting in Madrid

The study met its primary endpoint of improved systolic blood pressure (SBP) profile at 6 hours with the istaroxime group performing significantly better than the control group Increased SBP also persisted through 24 hours The study also met several key secondary endpoints associated with improving cardiac function Investor conference call […]

Positive Phase 3 study with aprocitentan demonstrates significant antihypertensive efficacy in patients with resistant hypertension

Ad hoc announcement pursuant to Art. 53 LR Aprocitentan reduces blood pressure compared to placebo by week 4 of treatment, the effect is maintained and confirmed over a period of 48 weeks, and is generally well tolerated with no major safety concerns Primary and key secondary endpoints were met with […]

Late-breaking Results Show Efficacy for CCM in Patients With HFpEF

Investigators Report Positive Findings From Feasibility Study of CCM in Heart Failure With Preserved Ejection Fraction at the European Society of Cardiology Heart Failure 2022 Congress MADRID and MARLTON, N.J., May 23, 2022 (GLOBE NEWSWIRE) — Impulse Dynamics, a global medical device company dedicated to improving the lives of people […]

Alnylam Presents New 18-Month Results from Exploratory Cardiac Endpoints in HELIOS-A Phase 3 Study of Investigational Vutrisiran

– New Exploratory Findings from 18-Month Analysis of HELIOS-A Suggest that Treatment with Investigational Vutrisiran May Benefit Patients with Hereditary ATTR (hATTR) Amyloidosis and Cardiac Involvement  – Improvements in NT-proBNP and Echocardiographic Parameters Seen in Cardiac Subpopulation  – Reductions in Technetium Uptake Observed in Patients with High Grade Uptake at […]

Daiichi Sankyo Europe highlights need to address the perception and classification of CVD risk with data presentations at EAS 2022

Latest data from the SANTORINI disease registry show that the cardiovascular (CV) risk of hypercholesterolaemia patients was underestimated considerably in the clinical setting.1,2,3 SANTORINI data show that nearly 80% of patients who are at high-risk or very high-risk of CV events do not attain guideline recommended low-density lipoprotein cholesterol (LDL-C) […]

Tenax Therapeutics Announces Successful Comparative Pharmacokinetic Study of TNX-201 for the Treatment of Pulmonary Arterial Hypertension

TNX-201 (oral imatinib modified release tablets) Formulation Development has been Successfully Completed Manufacturing Underway to Support Phase 3 PAH Study (IMPROVE) MORRISVILLE, N.C.–(BUSINESS WIRE)–Tenax Therapeutics, Inc. (Nasdaq: TENX), a specialty pharmaceutical company focused on identifying, developing and commercializing products that address cardiovascular and pulmonary diseases with high unmet medical need, […]

Vectorious Announces VECTOR-HF I Study Confirms Safety and Accuracy of V-LAP In-Heart Sensor for Left Atrial Pressure Management of Heart Failure

First clinical data of implantable heart sensor with remote measurement capabilities presented at prestigious Late-Breaking Science forum at the ESC Heart Failure 2022 TEL AVIV, Israel–(BUSINESS WIRE)–Vectorious Medical Technologies Ltd., an innovator in implantable hemodynamic monitoring in heart failure (HF), today announced results of VECTOR-HF I, a first-in-man clinical study […]

Innovative Medical 3D Printing at Tampa General Hospital and USF Health Morsani College of Medicine Provides Clearer Map for Surgery

Advanced techniques in 3D printing create replicas of organs to better inform physicians and patients and improve the safety and efficiency of procedures. TAMPA, Fla., May 19, 2022 /PRNewswire/ — How do you mend a broken heart? With plastic. That’s a goal at Tampa General Hospital, where a sophisticated 3D printing program is making replicas of human […]

PLx Pharma Inc. Showcases VAZALORE at The Annual Meeting of The Society for Cardiovascular Angiography and Interventions

VAZALORE Featured in Prominent Publication as Promising Alternative to Current Aspirin Options for Secondary Prevention of Cardiac Events SPARTA, N. J., May 20, 2022 (GLOBE NEWSWIRE) — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), is a commercial-stage drug delivery platform technology company focused on its clinically-validated and patent-protected […]

Shockwave IVL Coronary Studies Demonstrate Excellent PCI Outcomes in Both Women and Men at One Year

Findings Hold Promise for Female Patients with Calcified Coronary Artery Disease Who Previously Suffered Worse Safety Outcomes than Male Patients Undergoing Atherectomy SANTA CLARA, Calif., May 19, 2022 (GLOBE NEWSWIRE) — Shockwave Medical, Inc. (NASDAQ: SWAV), a pioneer in the development of Intravascular Lithotripsy (IVL) to treat severely calcified cardiovascular […]