ANGPTL3 Base Editor Delivered via Internally Developed GalNAc-LNPs Potently Reduced Blood ANGPTL3 Protein by 94-97% in a Novel NHP Model of Homozygous Familial Hypercholesterolemia GalNAc-LNP Delivery of ANGPTL3 Base Editor Led to Potent Editing in both LDLR-Deficient and Normal NHP Livers, Supporting Potential Broad Applicability CAMBRIDGE, Mass., Nov. 09, 2021 (GLOBE […]
Coronary/Structural Heart
Acarix accelerates US market entry with Proximo Medical as commercialization partner
Press release (MAR) Malmö, Sweden, November 9, 2021 Acarix accelerates US market entry with Proximo Medical as commercialization partner Acarix today announced the signing of a Commercial Access agreement with Proximo Medical, LLC, to rapidly initiate the commercialization of the CADScor system in the US market. With the agreement, Acarix immediately gains […]
Edwards Announces Six-month Data From Transcatheter Tricuspid Replacement Program
IRVINE, Calif., Nov. 6, 2021 /PRNewswire/ — Edwards Lifesciences Corporation (NYSE: EW) announced that results from a clinical trial of the company’s EVOQUE transcatheter tricuspid valve replacement system demonstrated that favorable patient outcomes were sustained at six months. Results from the TRISCEND study, treating patients with tricuspid regurgitation, were presented during the late-breaking clinical […]
Medtronic self-expanding TAVR platform shows excellent longer-term performance at five years in SURTAVI Trial
TCT 2021: Intermediate risk TAVR patients demonstrate strong hemodynamics and stable valve performance at five years DUBLIN and ORLANDO, Fla., Nov. 5, 2021 /PRNewswire/ — Medtronic plc (NYSE:MDT), a global leader in healthcare technology, today unveiled five-year clinical data from the Surgical Replacement and Transcatheter Aortic Valve Implantation (SURTAVI) Trial, which was presented as a Late […]
Imara to Report Data Demonstrating the Potential of Tovinontrine (IMR-687) for the Treatment of Heart Failure with Preserved Ejection Fraction (HFpEF)
Preclinical data from three different mouse models of HFpEF to be presented at American Heart Association (AHA) Scientific Sessions HFpEF development to be led by cardiologist Toni Bransford, M.D., FACC, FASE Imara’s new Vice President of Clinical Development BOSTON, Nov. 08, 2021 (GLOBE NEWSWIRE) — Imara Inc. (Nasdaq: IMRA), a clinical-stage […]
Ancora Heart AccuCinch® System Shows Positive 12-Month Outcomes in Multi-Study Analysis
Results Presented at Transcatheter Cardiovascular Therapeutics 2021 ORLANDO, Fla.–(BUSINESS WIRE)–Ancora Heart, Inc., a company developing a novel therapy to address heart failure, today announced results from an analysis of multiple studies that showed positive outcomes with its investigational AccuCinch® Ventricular Restoration System. The results were presented during a Featured Clinical Research […]
Empagliflozin shows consistent cardio-renal benefits in adults with heart failure with left ventricular ejection fraction over 40 percent regardless of chronic kidney disease status
– In a new sub-analysis of the landmark EMPEROR-Preserved® Phase III trial, empagliflozin reduced the combined relative risk of cardiovascular death and hospitalization for heart failure and slowed kidney function decline1 – Empagliflozin consistently improved outcomes across the full range of kidney function down to an eGFR of 20 mL/min/1.73 m2 1 INGELHEIM, […]
egnite, Inc. Presented New Data on the Use of Artificial Intelligence to Predict the Progression of Aortic Stenosis at TCT 2021 Conference
AI-powered algorithms are proven to accurately predict the likelihood a patient with moderate AS has progressed to severe AS. ALISO VIEJO, Calif.–(BUSINESS WIRE)–egnite, Inc. presented new data at the Transcatheter Cardiovascular Therapeutics (TCT) 2021 conference held November 4-6. The presentation showcased the proven accuracy and results of artificial intelligence (AI) […]
Shockwave Medical Unveils First One-Year Results of Coronary Intravascular Lithotripsy
New Data at TCT From the Disrupt CAD Clinical Program Demonstrate Consistency of Shockwave IVL Outcomes Over Time, Across Calcium Morphologies and Between Genders November 05, 2021 08:00 ET | Source: Shockwave Medical, Inc. SANTA CLARA, Calif., Nov. 05, 2021 (GLOBE NEWSWIRE) — Shockwave Medical, Inc. (NASDAQ: SWAV), a pioneer in the […]
Medicure Announces that the Shortened AGGRASTAT® Versus INTEGRILIN® in Percutaneous Coronary Intervention (SAVI-PCI) Study has Met its Primary Endpoint
WINNIPEG, MB, Nov. 4, 2021 /PRNewswire/ – Medicure Inc. (“Medicure” or the “Company”) (TSXV: MPH) (OTC: MCUJF), a cardiovascular pharmaceutical company, is pleased to announce the results from the SAVI-PCI clinical trial demonstrating that the use of short infusion AGGRASTAT® (tirofiban hydrochloride) injection was non-inferior to label-dosing INTEGRILIN® (eptifibatide) or long-infusion AGGRASTAT® in a primary […]



