Financial

Orchestra BioMed Announces Pricing of $40 Million Public Offering

NEW HOPE, Pa., Aug. 01, 2025 (GLOBE NEWSWIRE) — Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, “Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships, announced today the pricing of an underwritten public offering of 9,413,637 shares of its common stock at a price to the public of $2.75 per share and, in lieu of common stock to certain investors, pre-funded warrants to purchase 5,136,363 shares of its common stock at a price to the public of $2.7499 per pre-funded warrant, which represents the per share public offering price for the shares of common stock less the $0.0001 per share exercise price for each pre-funded warrant (the “Offering”). In addition, the Company granted the underwriters a 30-day option to purchase up to an additional 2,182,500 shares of its common stock at the public offering price per share, less underwriting discounts and commissions. All of the securities are being offered by the Company. The Offering is expected to close on August 4, 2025, subject to customary closing conditions. The gross proceeds from the Offering, before deducting underwriting discounts and commissions and estimated offering expenses, are expected to be approximately $40.0 million, assuming no exercise of the underwriters’ option. The Company intends to use the net proceeds from the Offering, together with its existing cash and cash equivalents, to fund the Company’s atrioventricular interval modulation (“AVIM”) therapy program and the execution of the BACKBEAT study and to fund its Virtue Sirolimus AngioInfusion Balloon (“SAB”) program and the planned Virtue SAB trial, as well as research and clinical development of other current or additional product candidates, and the remainder for working capital and other general corporate purposes. Piper Sandler and TD Cowen are acting as joint book-running managers for the Offering. The securities described above are being offered pursuant to a shelf registration statement on Form S-3 (File No. 333-279430) that was filed with the Securities and Exchange Commission (the “SEC”) on May 15, 2024 and declared effective on May 24, 2024. A preliminary prospectus supplement relating to the Offering has been, and a prospectus supplement relating to the Offering will be, filed with the SEC. The Offering is being made only by means of a prospectus supplement and an accompanying prospectus that form a part of the registration statement. Copies of the prospectus supplement and accompanying prospectus relating to the Offering may be obtained free of charge on the SEC’s website located at www.sec.gov. Copies of the prospectus supplement and accompanying prospectus relating to the Offering may also be obtained, when available, from: Piper Sandler & Co., Attention: Prospectus Department, 350 North 5th Street, Suite 1000, Minneapolis, MN 55401, or by telephone at (800) 747-3924, or by email at prospectus@psc.com; or TD Securities (USA) LLC, 1 Vanderbilt Avenue, New York, New York 10017, by telephone at (833) 297-2926, or by email at TD.ECM_Prospectus@tdsecurities.com. This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation, or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction. About Orchestra BioMed Orchestra BioMed (Nasdaq: OBIO) is a biomedical innovation company accelerating high-impact technologies to patients through risk-reward sharing partnerships with leading medical device companies. Orchestra BioMed’s partnership-enabled business model focuses on forging strategic collaborations with leading medical device companies to drive successful global commercialization of products it develops. Orchestra BioMed’s lead product candidate is AVIM therapy for the treatment of hypertension, the leading risk factor for death worldwide. Orchestra BioMed is also developing Virtue SAB for the treatment of atherosclerotic artery disease, the leading cause of mortality worldwide. Orchestra BioMed has a strategic collaboration with Medtronic, one of the largest medical device companies in the world, for development and commercialization of AVIM therapy for the treatment of hypertension in pacemaker-indicated patients, and a strategic partnership with Terumo, a global leader in medical technology, for development and commercialization of Virtue SAB for the treatment of artery disease. The Company has received four Breakthrough Device Designations from the U.S. Food and Drug Administration across these two core programs, reflecting the significant potential of its technologies to address high unmet needs in cardiovascular care. Forward-Looking Statements Certain statements included in this press release that are not historical facts are forward-looking statements for purposes of the safe harbor provisions under the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements generally are accompanied by words such as “believe,” “may,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “expect,” “should,” “would,” “plan,” “predict,” “potential,” “seem,” “seek,” “future,” “outlook” and similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements include, but are not limited to, statements regarding the proposed Offering, including the completion and timing of the Offering and the anticipated use of proceeds from the Offering. These statements are based on various assumptions, whether or not identified in this press release, and on the current expectations of the Company’s management and are not predictions of actual performance. These forward-looking statements are provided for illustrative purposes only and are not intended to serve as and must not be relied on as a guarantee, an assurance, a prediction, or a definitive statement of fact or probability. Actual events and circumstances are difficult or impossible to predict and may differ from assumptions. Many actual events and circumstances are beyond the control of the Company. These forward-looking statements are subject to a number of risks and uncertainties, including changes in domestic and foreign business, market, financial, political, and legal conditions; risks related to regulatory approval of the Company’s commercial product candidates and ongoing regulation of the Company’s product candidates, if approved; the timing of, and the Company’s ability to achieve expected regulatory and business milestones; the impact of competitive products and product candidates; and the risk factors discussed under the heading “Item 1A. Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2024, which was filed with the SEC on March 31, 2025, and the risk factor discussed under the heading “Item 1A. Risk Factors” in the Company’s Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2025, which was filed with the SEC on May 12, 2025, as such discussion may be updated from time to time by subsequent filings the Company may make with the SEC, as well as the risks identified in the registration statement and the preliminary prospectus supplement relating to the Offering. The Company operates in a very competitive and rapidly changing environment. New risks emerge from time to time. Given these risks and uncertainties, the Company cautions against placing undue reliance on these forward-looking statements, which only speak as of the date of this press release. The Company does not plan and undertakes no obligation to update any of the forward-looking statements made herein, except as required by law. Investor ContactSilas NewcombOrchestra BioMedSnewcomb@orchestrabiomed.com Media ContactKelsey Kirk-EllisOrchestra BioMedKkirkellis@orchestrabiomed.com

Ligand and Medtronic Commit $70 Million in Strategic Capital to Orchestra BioMed

• Ligand to invest $35 million in exchange for a tiered royalty on future sales of Orchestra’s AVIM therapy and Virtue SAB and an additional $5 million in an equity private placement • Medtronic to invest $10 million in an equity private placement and an additional $20 million in a secured subordinated promissory note convertible to prepaid revenue share • Medtronic and Orchestra BioMed expand strategic collaboration to provide pathway for development of AVIM therapy-enabled leadless pacemakers NEW HOPE, Pa., July 31, 2025 (GLOBE NEWSWIRE) — Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, “Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships, today announced that the Company has secured $70 million in new capital from Ligand Pharmaceuticals Incorporated (Nasdaq: LGND, “Ligand”) and Medtronic, plc. (NYSE: MDT, “Medtronic”) to advance its late-stage partnered cardiology programs.   Simultaneously, Orchestra BioMed and Medtronic, which have an existing strategic collaboration for atrioventricular interval modulation (“AVIM”) therapy for the treatment of uncontrolled hypertension in pacemaker-indicated patients, have amended their agreement to include the potential future development of AVIM therapy-enabled leadless pacemakers. Unlike traditional pacemakers that are placed in a patient’s chest with leads (or wires) running to the heart, minimally-invasive Medtronic Micra™ leadless pacemakers are implanted directly into the heart, reducing potential sources of complications. Ligand $40 million Investment Todd Davis, Chief Executive Officer of Ligand commented: “We are pleased to partner with Medtronic and Orchestra BioMed in this important endeavor. This investment expands our pipeline of development-stage products and demonstrates our confidence in Orchestra BioMed’s scientific advancements, as well as the strong capabilities of its partner, Medtronic. We are proud to support Orchestra BioMed as they develop novel high-impact, device-based therapies such as AVIM therapy and Virtue SAB targeting high-risk patient populations with hypertension and arterial disease, two of the most significant global health challenges.” David Hochman, Chairman and Chief Executive Officer of Orchestra BioMed stated, “Ligand has been one of the inspirations for our partnership-driven approach to creating long-term, capital-efficient value through royalty-based collaborations. We are thrilled to welcome them as a strategic capital partner. Ligand’s decision to invest in our partnered programs and our team reflects our shared conviction in the transformative potential of both AVIM therapy and Virtue SAB – our late-stage flagship technologies aimed to address important unmet medical needs in large, established global markets. This transaction provides foundational financial support to enable our potential achievement of key value creating milestones for both of our high-impact clinical programs.” Under the terms of the agreement, Ligand will pay $20 million to Orchestra BioMed at closing with an additional $15 million to be funded, subject to certain conditions precedent, at the nine-month anniversary of the transaction closing date. Ligand has also agreed to invest an additional $5 million to purchase shares of the Company’s common stock in an equity private placement at the public offering price per share in Orchestra BioMed’s next public offering of its equity securities. In exchange, Ligand will receive a low double-digit royalty on the first $100 million in commercial revenues from Orchestra’s AVIM therapy and Virtue SAB programs in all indications. Ligand will also earn a mid-single-digit royalty on annual revenues exceeding $100 million in commercial revenues from AVIM therapy in the uncontrolled hypertension and increased cardiovascular risk indication and Virtue SAB in coronary artery disease indications. Medtronic $30 million Additional Investment & Future Leadless AVIM Therapy Device Development Robert C. Kowal, M.D., Ph.D., Vice President and General Manager of Cardiac Pacing Therapies within the Medtronic Cardiac Rhythm Management operating unit, commented: “Our expanded investment in Orchestra BioMed reflects confidence in their clinical progress. Broadening our collaboration to include integrating AVIM therapy into future leadless pacing technology reaffirms our commitment to transform care for patients who need pacing therapy and have uncontrolled hypertension.” Mr. Hochman added, “Medtronic continues to be an outstanding partner for the AVIM therapy program. We believe their $30 million additional commitment to Orchestra BioMed reflects their belief in the clinical and commercial potential for this therapy to benefit patients with uncontrolled hypertension and increased cardiovascular risk in the pacemaker population. Expanding our existing collaboration to provide for potential future integration of AVIM therapy into a leadless pacemaker system deepens our strategic alignment and creates a potential pathway for patients to benefit from both AVIM therapy and cutting-edge leadless pacing technology, simultaneously.” Subject to the terms of the agreement, Medtronic’s $30 million additional investment commitment to Orchestra BioMed includes a $10 million agreement to purchase shares of the Company’s common stock in a private placement at the public offering price in the Company’s next public offering of its equity securities. Medtronic also made a $20 million commitment to purchase a five-year term secured subordinated promissory note, to be funded in nine months which automatically converts to a prepaid revenue share upon U.S. Food and Drug Administration (“FDA”) approval of AVIM therapy. The prepaid revenue share will be credited back to Medtronic at a low double-digit percentage of actual AVIM therapy revenue share paid to Orchestra BioMed, up to $40 million in cumulative revenue share. About Ligand PharmaceuticalsLigand is a biopharmaceutical company enabling scientific advancement through supporting the clinical development of high-value medicines. Ligand does this by providing financing, licensing our technologies or both. Ligand’s business model seeks to generate value for stockholders by creating a diversified portfolio of biotech and pharmaceutical product revenue streams that are supported by an efficient and low corporate cost structure. Ligand’s goal is to offer investors an opportunity to participate in the promise of the biotech industry in a profitable and diversified manner. Ligand’s business model is based on funding programs in mid- to late-stage drug development in return for economic rights, purchasing royalty rights in development stage or commercial biopharmaceutical products and licensing its technology to help partners discover and develop medicines. Ligand partners with other pharmaceutical companies to attempt to leverage what they do best (late-stage development, regulatory management and commercialization) in order to generate revenue. Ligand operates two infrastructure-light royalty generating technology IP platform technologies. Ligand’s Captisol® platform technology is a chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs. Ligand’s NITRICIL™ platform technology facilitates tunable dosing, permitting an adjustable drug release profile to allow proprietary formulations that target a broad range of indications. Ligand has established multiple alliances, licenses and other business relationships with the world’s leading pharmaceutical companies including Amgen, Merck, Pfizer, Jazz, Gilead Sciences and Baxter International. For more information, please visit www.ligand.com. Follow Ligand on X and LinkedIn. Ligand uses its investor relations website and X as a means of disclosing material non-public information and for complying with our disclosure obligations under Regulation FD. Investors should monitor our website and our X account, in addition to following our press releases, SEC filings, public conference calls and webcasts. About Orchestra BioMed Orchestra BioMed (Nasdaq: OBIO) is a biomedical innovation company accelerating high-impact technologies to patients through risk-reward sharing partnerships with leading medical device companies. Orchestra BioMed’s partnership-enabled business model focuses on forging strategic collaborations with leading medical device companies to drive successful global commercialization of products it develops. Orchestra BioMed’s lead product candidate is AVIM therapy for the treatment of hypertension, the leading risk factor for death worldwide. Orchestra BioMed is also developing Virtue SAB for the treatment of atherosclerotic artery disease, the leading cause of mortality worldwide. Orchestra BioMed has a strategic collaboration with Medtronic, one of the largest medical device companies in the world, for development and commercialization of AVIM therapy for the treatment of hypertension in pacemaker-indicated patients, and a strategic partnership with Terumo, a global leader in medical technology, for development and commercialization of Virtue SAB for the treatment of artery disease. The Company has received four Breakthrough Device Designations from the FDA across these two core programs, reflecting the significant potential of its technologies to address high unmet needs in cardiovascular care. For further information about Orchestra BioMed, please visit www.orchestrabiomed.com, and follow us on LinkedIn. References to Websites and Social Media Platforms References to information included on, or accessible through, websites and social media platforms do not constitute incorporation by reference of the information contained at or available through such websites or social media platforms, and you should not consider such information to be part of this press release. About AVIM Therapy AVIM therapy is an investigational therapy compatible with standard dual-chamber pacemakers designed to substantially and persistently lower blood pressure. It has been evaluated in pilot studies in patients with hypertension who are also indicated for a pacemaker. MODERATO II, a double-blind, randomized pilot study, showed that patients treated with AVIM therapy experienced net reductions of 8.1 mmHg in 24-hour ambulatory systolic blood pressure (aSBP) and 12.3 mmHg in office systolic blood pressure (oSBP) at six months when compared to control patients. In addition to reducing blood pressure, clinical results using AVIM therapy demonstrate improvements in cardiac function and hemodynamics. The BACKBEAT (BradycArdia paCemaKer with atrioventricular interval modulation for Blood prEssure treAtmenT) global pivotal study will further evaluate the safety and efficacy of AVIM therapy in lowering blood pressure in patients who have systolic blood pressure above target despite anti-hypertensive medication and who are indicated for or have recently received a dual-chamber cardiac pacemaker. AVIM therapy has been granted Breakthrough Device Designation by the FDA for the treatment of uncontrolled hypertension in patients who have increased cardiovascular risk. About Virtue SABVirtue SAB is designed to deliver a proprietary extended-release formulation of sirolimus, SirolimusEFR™ through a non-coated microporous AngioInfusion™ Balloon that protects the drug in transit to consistently deliver a large liquid dose overcoming certain limitations of drug-coated balloons. SirolimusEFR delivered by Virtue SAB has been shown in published preclinical series involving hundreds of arterial deliveries to achieve sustained tissue levels well above the known required therapeutic tissue concentration for inhibiting restenosis (1 ng/mg tissue) for the entire critical healing period of approximately 30 days. Virtue SAB demonstrated positive three-year clinical data in coronary ISR in the SABRE study, a multi-center prospective, independent core lab-adjudicated clinical study of 50 patients conducted in Europe. Virtue SAB has been granted Breakthrough Device Designation by the FDA for specific indications relating to coronary ISR, coronary small vessel disease and peripheral artery disease below-the-knee. Forward-Looking Statements Certain statements included in this press release that are not historical facts are forward-looking statements for purposes of the safe harbor provisions under the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements generally are accompanied by words such as “believe,” “may,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “expect,” “should,” “would,” “plan,” “predict,” “potential,” “seem,” “seek,” “future,” “outlook” and similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements include, but are not limited to, statements relating to the enrollment, implementation and design of the Company’s planned and ongoing pivotal trials, realizing the clinical and commercial value of the Company’s product candidates, the potential safety and efficacy of the Company’s product candidates, the ability of the Company’s partnerships to accelerate clinical development, and the Company’s ability to satisfy funding and closing conditions of the transactions described in this press release. These statements are based on various assumptions, whether or not identified in this press release, and on the current expectations of the Company’s management and are not predictions of actual performance. These forward-looking statements are provided for illustrative purposes only and are not intended to serve as and must not be relied on as a guarantee, an assurance, a prediction, or a definitive statement of fact or probability. Actual events and circumstances are difficult or impossible to predict and may differ from assumptions. Many actual events and circumstances are beyond the control of the Company. These forward-looking statements are subject to a number of risks and uncertainties, including changes in domestic and foreign business, market, financial, political, and legal conditions; risks related to regulatory approval of the Company’s commercial product candidates and ongoing regulation of the Company’s product candidates, if approved; the timing of, and the Company’s ability to achieve expected regulatory and business milestones; the impact of competitive products and product candidates; and the risk factors discussed under the heading “Item 1A. Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2024, which was filed with the SEC on March 31, 2025 and the risk factor discussed under the heading “Item 1A. Risk Factors” in the Company’s Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2025, which was filed with the SEC on May 12, 2025. The Company operates in a very competitive and rapidly changing environment. New risks emerge from time to time. Given these risks and uncertainties, the Company cautions against placing undue reliance on these forward-looking statements, which only speak as of the date of this press release. The Company does not plan and undertakes no obligation to update any of the forward-looking statements made herein, except as required by law. Contacts For Orchestra BioMed:Investors:Silas NewcombSnewcomb@orchestrabiomed.com Media: Kelsey Kirk-EllisKkirkellis@orchestrabiomed.com For Ligand:Investors:Melanie Hermaninvestors@ligand.com(858) 550-7761 Media:Kellie Walshmedia@ligand.com(914) 315-6072

InspireMD Announces the Appointment of Raymond W. Cohen to its Board of Directors

MIAMI, July 31, 2025 (GLOBE NEWSWIRE) — InspireMD, Inc. (Nasdaq: NSPR) (“InspireMD” or the “Company”), developer of the CGuard® Prime carotid stent system for the prevention of stroke, today announced the appointment of Raymond W. Cohen to its Board of Directors. Mr. Cohen has over 40 years of leadership experience in medical technology with a successful track record of scaling commercial operations and creating shareholder value through market leadership and successful exit transactions.

Merit Medical Reports Second Quarter 2025 Results and Updates Full-Year Guidance

Highlights† Reported revenue of $382.5 million, up 13.2%Constant currency revenue* and constant currency revenue, organic* up 12.5% and up 6.7%, respectivelyGAAP operating margin of 12.3%, compared to 13.6% in prior year periodNon-GAAP operating margin* of 21.2%, compared to 20.1% in prior year periodGAAP EPS $0.54, down 11.6%Non-GAAP EPS* $1.01, up 9.8%Free cash flow* generation of $89.1 million over first six months of 2025, up 8.1% year-over-yearAcquired Biolife Delaware, L.L.C. (“Biolife”), a manufacturer of hemostatic devices branded as StatSeal® and WoundSeal®Martha Aronson named as new President and Chief Executive Officer, effective October 3, 2025 † Comparisons above are calculated for the current quarter compared with the second quarter of 2024, unless otherwise specified. Amounts stated in this release are rounded, while percentages are calculated from the underlying amounts. * Constant currency revenue; constant currency revenue, organic; non-GAAP gross profit and margin; non-GAAP operating income and margin; non-GAAP net income; non-GAAP EPS; and free cash flow figures (used here and below) are non-GAAP financial measures. A reconciliation of these financial measures to their most directly comparable GAAP financial measures is included under the heading “Non-GAAP Financial Measures” below. SOUTH JORDAN, Utah, July 30, 2025 (GLOBE NEWSWIRE) — Merit Medical Systems, Inc. (NASDAQ: MMSI), a leading global manufacturer and marketer of healthcare technology, today announced revenue of $382.5 million for the quarter ended June 30, 2025, an increase of 13.2% compared to the quarter ended June 30, 2024. Constant currency revenue for the second quarter of 2025 increased 12.5% compared to the prior year period and constant currency revenue, organic, for the second quarter of 2025 increased 6.7% compared to the prior year period. “We delivered better-than-expected financial performance in the second quarter, with our top-and-bottom line results exceeding the high-end of our forecast,” said Fred P. Lampropoulos, Merit’s Chairman and Chief Executive Officer. “We have increased our 2025 revenue and non-GAAP earnings per share guidance to reflect our stronger-than-expected first half financial results and our updated profitability expectations for the balance of the year. Specifically, we believe we can deliver higher non-GAAP gross and non-GAAP operating margins on a year-over-year basis in 2025, largely due to our currently projected impact of implemented trade policies and related actions by the U.S. and other countries since our first quarter report.” Mr. Lampropoulos continued: “We are proud of the strong financial results over the first half of the year where we delivered constant currency, organic, growth of more than 6%, non-GAAP EPS growth of 12% and we generated more than $89 million of free cash flow. Our updated guidance reflects continued confidence in our team’s ability to deliver strong execution, stable constant currency growth, improving profitability and solid cash flow generation this year.” Merit’s revenue by operating segment and product category for the three and six-month periods ended June 30, 2025 and 2024 was as follows (unaudited; in thousands, except for percentages):      Three Months Ended   Reported    Constant Currency*     June 30,     Impact of foreign June 30,         2025    2024(1) % Change exchange 2025 % ChangeCardiovascular                  Peripheral Intervention $142,847 $134,386 6.3%   $(620) $142,227 5.8%  Cardiac Intervention  115,251  93,307 23.5%    (844)  114,407 22.6%  Custom Procedural Solutions  53,634  50,132 7.0%    (637)  52,997 5.7%  OEM  52,293  49,990 4.6%    (142)  52,151 4.3%  Total  364,025  327,815 11.0%    (2,243)  361,782 10.4%                     Endoscopy                  Endoscopy Devices  18,437  10,188 81.0%    (14)  18,423 80.8%                     Total $382,462 $338,003 13.2%   $(2,257) $380,205 12.5%        Six Months Ended   Reported    Constant Currency *     June 30,     Impact of foreign June 30,         2025    2024(1) % Change exchange 2025 % ChangeCardiovascular                  Peripheral Intervention $280,126 $264,452 5.9%   $1,046  $281,172 6.3%  Cardiac Intervention  214,992  183,483 17.2%    389   215,381 17.4%  Custom Procedural Solutions  101,576  98,655 3.0%    (225)  101,351 2.7%  OEM  106,044  94,599 12.1%    (71)  105,973 12.0%  Total  702,738  641,189 9.6%    1,139   703,877 9.8%                     Endoscopy                  Endoscopy Devices  35,075  20,322 72.6%    9   35,084 72.6%                     Total $737,813 $661,511 11.5%   $1,148  $738,961 11.7%   (1)Commencing January 1, 2025, we reorganized our sales teams and product categories to include revenues from the sale of our spine devices under our OEM product category. Revenue figures for 2024 have been recast to reflect this realignment of our portfolio of spine products, representing approximately $5.7 million and $11.0 million in revenue for the three and six-month periods ended June 30, 2024, within the OEM product category to provide comparability between the reported periods.   Merit’s GAAP gross margin for the second quarter of 2025 was 48.2%, compared to GAAP gross margin of 47.7% for the second quarter of 2024. Merit’s non-GAAP gross margin* for the second quarter of 2025 was 53.2%, compared to non-GAAP gross margin* of 51.5% for the second quarter of 2024. Merit’s GAAP net income for the second quarter of 2025 was $32.6 million, or $0.54 per share, compared to GAAP net income of $35.7 million, or $0.61 per share, for the second quarter of 2024. Merit’s non-GAAP net income* for the second quarter of 2025 was $61.0 million, or $1.01 per share, compared to non-GAAP net income* of $53.8 million, or $0.92 per share, for the second quarter of 2024. As of June 30, 2025, Merit had cash and cash equivalents of $341.8 million and total debt obligations of $747.5 million, compared to cash and cash equivalents of $376.7 million and total debt obligations of $747.5 million as of December 31, 2024. Merit had available borrowing capacity of approximately $697 million as of June 30, 2025. Fiscal Year 2025 Financial Guidance Based upon the information currently available to Merit’s management, for the year ending December 31, 2025, absent the potential impact of trade policies and related actions implemented by the U.S. and other countries subsequent to today’s date, material acquisitions, non-recurring transactions or other factors beyond Merit’s current expectations, Merit anticipates the following financial results: Revenue and Earnings Guidance*            Updated GuidancePrior Guidance(2)Financial Measure Year Ending% Change Year Ending% Change   December 31, 2025Y/YDecember 31, 2025Y/Y      Net Sales $1.495 – $1.507 billion10% – 11%$1.480 – $1.501 billion9% – 11%Cardiovascular Segment $1.423 – $1.434 billion9% – 10%$1.407 – $1.426 billion8% – 10%Endoscopy Segment $72.0 – $73.0 million32% – 34%$73.0 – $75.0 million34% – 37%      Non-GAAP       Earnings Per Share(1) $3.52 – $3.722% – 8%$3.28 – $3.41(5%) – (1%) *Percentage figures approximated; dollar figures may not foot due to rounding(1) Merit’s non-GAAP earnings per share reflect the dilutive impact of its 3.00% Convertible Senior Notes due 2029 (the “Convertible Notes”) calculated using the if-converted method of approximately $0.05 per share for the year ending December 31, 2025. Any offsetting impacts of the capped call associated with the Convertible Notes are not considered.(2) “Prior Guidance” reflects Merit’s full-year 2025 financial guidance, previously introduced on May 20, 2025. 2025 Net Sales Guidance – % Change from Prior Year (Constant Currency) Reconciliation*            Updated Guidance Prior Guidance(1)  Low High Low High2025 Net Sales Guidance – % Change from Prior Year (GAAP) 10.2% 11.1% 9.1% 10.7%Estimated impact of foreign currency exchange rate fluctuations (0.5%) (0.5%) 0.4% 0.4%2025 Net Sales Guidance – % Change from Prior Year (Constant Currency) 9.7% 10.6% 9.5% 11.0% *Percentage figures approximated and may not foot due to rounding(1)“Prior Guidance” reflects Merit’s full-year 2025 financial guidance, previously introduced on May 20, 2025. Merit does not provide guidance for GAAP reported financial measures (other than revenue) or a reconciliation of forward-looking non-GAAP financial measures to the most directly comparable GAAP reported financial measures (other than revenue) because Merit is unable to predict with reasonable certainty the financial impact of various items which could impact Merit’s future financial results, such as expenses attributable to acquisitions or other extraordinary transactions, non-cash expenses related to amortization or write-off of previously acquired tangible and intangible assets, certain employee termination benefits, performance-based stock compensation expenses, expenses resulting from non-ordinary course litigation or administrative proceedings and resulting settlements, governmental proceedings, and changes in governmental or industry regulations. These items are uncertain, depend on various factors, and could have a material impact on GAAP reported results for the guidance period. For the same reasons, Merit is unable to address the significance of the unavailable information, which could be material to future results. Specifically, Merit is not, without unreasonable effort, able to reliably predict the impact of these items and Merit believes inclusion of a reconciliation of these forward-looking non-GAAP measures to their GAAP counterparts could be confusing to investors or cause undue reliance. Merit’s financial guidance for the year ending December 31, 2025 is subject to risks and uncertainties identified in this release and Merit’s filings with the U.S. Securities and Exchange Commission (the “SEC”). This guidance is based on information and estimates available to Merit as of July 30, 2025. Should known or unknown risks or uncertainties materialize or should underlying assumptions prove inaccurate, actual results will likely vary, and could vary materially, from past results and those anticipated, estimated or projected. CONFERENCE CALL Merit will hold its investor conference call today, Wednesday, July 30, 2025, at 5:00 p.m., Eastern Time. To access the conference call, please pre-register using the following link. Registrants will receive confirmation with dial-in details. A live webcast and slide deck will also be available at merit.com. CONSOLIDATED BALANCE SHEETS(in thousands)            June 30,         2025 December 31,   (Unaudited) 2024ASSETS        Current Assets        Cash and cash equivalents $341,819  $376,715 Trade receivables, net  204,162   190,243 Other receivables  14,292   16,588 Inventories  323,309   306,063 Prepaid expenses and other assets  30,162   28,544 Prepaid income taxes  3,543   3,286 Income tax refund receivables  5,785   2,335 Total current assets  923,072   923,774        Property and equipment, net  409,985   386,165 Intangible assets, net  562,158   498,265 Goodwill  504,555   463,511 Deferred income tax assets  16,243   16,044 Operating lease right-of-use assets  89,279   65,508 Other assets  80,753   65,336 Total Assets $2,586,045  $2,418,603        LIABILITIES AND STOCKHOLDERS’ EQUITY        Current Liabilities        Trade payables $69,066  $68,502 Accrued expenses  140,204   134,077 Current operating lease liabilities  10,262   10,331 Income taxes payable  6,040   3,492 Total current liabilities  225,572   216,402        Long-term debt  731,795   729,551 Deferred income tax liabilities  26,925   240 Liabilities related to unrecognized tax benefits  2,169   2,118 Deferred compensation payable  19,800   19,197 Deferred credits  1,450   1,502 Long-term operating lease liabilities  78,496   54,783 Other long-term obligations  11,790   15,451 Total liabilities  1,097,997   1,039,244        Stockholders’ Equity        Common stock  734,841   703,219 Retained earnings  758,269   695,541 Accumulated other comprehensive loss  (5,062)  (19,401)Total stockholders’ equity  1,488,048   1,379,359 Total Liabilities and Stockholders’ Equity $2,586,045  $2,418,603           CONSOLIDATED STATEMENTS OF INCOME(Unaudited, in thousands except per share amounts)                  Three Months Ended     Six Months Ended   June 30,  June 30,      2025     2024     2025     2024 Net sales $382,462  $338,003  $737,813  $661,511 Cost of sales  197,975   176,903   381,306   348,696 Gross profit  184,487   161,100   356,507   312,815              Operating expenses:                Selling, general and administrative  113,097   94,585   220,583   189,013 Research and development  24,367   20,263   46,845   41,745 Contingent consideration expense  143   306   1,166   189 Total operating expenses  137,607   115,154   268,594   230,947              Income from operations  46,880   45,946   87,913   81,868              Other income (expense):                Interest income  3,761   7,561   7,551   14,837 Interest expense  (6,775)  (7,679)  (13,343)  (15,725)Other income (expense) — net  (487)  15   (784)  (789)Total other expense — net  (3,501)  (103)  (6,576)  (1,677)             Income before income taxes  43,379   45,843   81,337   80,191              Income tax expense  10,798   10,117   18,609   16,225              Net income $32,581  $35,726  $62,728  $63,966              Earnings per common share                Basic $0.55  $0.61  $1.06  $1.10 Diluted $0.54  $0.61  $1.03  $1.09              Weighted average shares outstanding                Basic  59,140   58,139   59,019   58,049 Diluted  60,611   58,740   60,945   58,653                   CONSOLIDATED STATEMENTS OF CASH FLOWS(Unaudited, in thousands)         Six Months Ended   June 30,      2025     2024 CASH FLOWS FROM OPERATING ACTIVITIES:    Net income $62,728  $63,966 Adjustments to reconcile net income to net cash provided by operating activities:        Depreciation and amortization  60,313   47,690 Gain on disposition of a business  (249)  — Write-off of certain intangible assets and other long-term assets  82   280 Amortization of right-of-use operating lease assets  5,766   6,063 Fair value adjustments related to contingent consideration liabilities  1,166   189 Stock-based compensation expense  19,951   12,245 Other adjustments  3,091   2,981 Changes in operating assets and liabilities, net of acquisitions  (28,969)  (28,692)Total adjustments  61,151   40,756 Net cash, cash equivalents, and restricted cash provided by operating activities  123,879   104,722        CASH FLOWS FROM INVESTING ACTIVITIES:        Capital expenditures for property and equipment  (34,812)  (22,309)Cash paid for notes receivable and other investments  (14,617)  (9,723)Cash paid in acquisitions, net of cash acquired  (122,555)  (4,932)Other investing, net  (1,002)  (1,574)Net cash, cash equivalents, and restricted cash used in investing activities  (172,986)  (38,538)       CASH FLOWS FROM FINANCING ACTIVITIES:    Proceeds from issuance of common stock  20,014   10,931 Proceeds from (payments on) long-term debt  —   (24,063)Contingent payments related to acquisitions  (2,567)  (142)Payment of taxes related to an exchange of common stock  (6,145)  (1,592)Net cash, cash equivalents, and restricted cash provided by (used in) financing activities  11,302   (14,866)Effect of exchange rates on cash  2,953   (1,750)Net increase (decrease) in cash, cash equivalents and restricted cash  (34,852)  49,568        CASH, CASH EQUIVALENTS AND RESTRICTED CASH:        Beginning of period  378,767   589,144 End of period $343,915  $638,712        RECONCILIATION OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH TO THE CONSOLIDATED BALANCE SHEETS:      Cash and cash equivalents  341,819   636,658 Restricted cash reported in prepaid expenses and other current assets  2,096   2,054 Total cash, cash equivalents and restricted cash $343,915  $638,712           Non-GAAP Financial Measures Although Merit’s financial statements are prepared in accordance with accounting principles generally accepted in the United States of America (“GAAP”), Merit’s management believes that the non-GAAP financial measures referenced in this release may provide investors with useful information regarding the underlying business trends and performance of Merit’s ongoing operations and can be useful for period-over-period comparisons of such operations. Non-GAAP financial measures used in this release include: constant currency revenue;constant currency revenue, organic;non-GAAP gross profit and margin;non-GAAP operating income and margin;non-GAAP net income;non-GAAP earnings per share; andfree cash flow. Merit’s management team uses these non-GAAP financial measures to evaluate Merit’s profitability and efficiency, to compare operating and financial results to prior periods, to evaluate changes in the results of its operating segments, and to measure and allocate financial resources internally. However, Merit’s management does not consider such non-GAAP measures in isolation or as an alternative to measures determined in accordance with GAAP. Readers should consider non-GAAP measures used in this release in addition to, not as a substitute for, financial reporting measures prepared in accordance with GAAP. These non-GAAP financial measures generally exclude some, but not all, items that may affect Merit’s net income. In addition, they are subject to inherent limitations as they reflect the exercise of judgment by management about which items are excluded. Merit believes it is useful to exclude such items in the calculation of non-GAAP gross profit and margin, non-GAAP operating income and margin, non-GAAP net income, and non-GAAP earnings per share (in each case, as further illustrated in the reconciliation tables below) because such amounts in any specific period may not directly correlate to the underlying performance of Merit’s business operations and can vary significantly between periods as a result of factors such as acquisition or other extraordinary transactions, non-cash expenses related to amortization or write-off of previously acquired tangible and intangible assets, certain employee termination benefits, expenses resulting from non-ordinary course litigation or administrative proceedings and resulting settlements, governmental proceedings or changes in tax or industry regulations, gains or losses on disposal of certain assets, and debt issuance costs. Merit may incur similar types of expenses in the future, and the non-GAAP financial information included in this release should not be viewed as a statement or indication that these types of expenses will not recur. Additionally, the non-GAAP financial measures used in this release may not be comparable with similarly titled measures of other companies. Merit urges readers to review the reconciliations of its non-GAAP financial measures to their most directly comparable GAAP financial measures included herein, and not to rely on any single financial measure to evaluate Merit’s business or results of operations. Constant Currency Revenue Merit’s constant currency revenue is prepared by converting the current-period reported revenue of subsidiaries whose functional currency is a currency other than the U.S. dollar at the applicable foreign exchange rates in effect during the comparable prior-year period and adjusting for the effects of hedging transactions on reported revenue, which are recorded in the U.S. dollar. The constant currency revenue adjustments of ($2.3) million and $1.1 million to reported revenue for the three and six-month periods ended June 30, 2025, respectively, were calculated using the applicable average foreign exchange rates for the three and six-month periods ended June 30, 2024. Constant Currency Revenue, Organic Merit’s constant currency revenue, organic, is defined, with respect to prior fiscal year periods, as GAAP revenue. With respect to current fiscal year periods, constant currency revenue, organic, is defined as constant currency revenue (as defined above), less revenue from certain acquisitions. For the three and six-month periods ended June 30, 2025, Merit’s constant currency revenue, organic, excludes revenues attributable to (i) the acquisition of Biolife in May 2025, (ii) the assets acquired from Cook Medical Holdings, LLC (“Cook Medical”) in November 2024 and (iii) the assets acquired from EndoGastric Solutions, Inc. in July 2024. Non-GAAP Gross Profit and Margin Non-GAAP gross profit is calculated by reducing GAAP cost of sales by amounts recorded for amortization of intangible assets and inventory mark-up related to acquisitions. Non-GAAP gross margin is calculated by dividing non-GAAP gross profit by reported net sales. Non-GAAP Operating Income and Margin Non-GAAP operating income is calculated by adjusting GAAP operating income for certain items which are deemed by Merit’s management to be outside of core operations and vary in amount and frequency among periods, such as expenses related to acquisitions or other extraordinary transactions, non-cash expenses related to amortization or write-off of previously acquired tangible and intangible assets, certain employee termination benefits, performance-based stock compensation expenses, expenses resulting from non-ordinary course litigation or administrative proceedings and resulting settlements, governmental proceedings, and changes in governmental or industry regulations, as well as other items referenced in the tables below. Non-GAAP operating margin is calculated by dividing non-GAAP operating income by reported net sales. Non-GAAP Net Income Non-GAAP net income is calculated by adjusting GAAP net income for the items set forth in the definition of non-GAAP operating income above, as well as for expenses related to debt issuance costs, gains or losses on disposal of certain assets, and other items set forth in the tables below. Non-GAAP EPS Non-GAAP EPS is defined as non-GAAP net income divided by the diluted shares outstanding for the corresponding period. Free Cash Flow Free cash flow is defined as cash flow from operations calculated in accordance with GAAP, less capital expenditures for property and equipment calculated in accordance with GAAP, as set forth in the consolidated statement of cash flows. Other Non-GAAP Financial Measure Reconciliations The following tables set forth supplemental financial data and corresponding reconciliations of non-GAAP financial measures to Merit’s corresponding financial measures prepared in accordance with GAAP, in each case, for the three and six-month periods ended June 30, 2025 and 2024. The non-GAAP income adjustments referenced in the following tables do not reflect non-performance-based stock compensation expense of $5.0 million and $3.4 million for the three-month periods ended June 30, 2025 and 2024, respectively and $9.3 million and $6.5 million for the six-month periods ended June 30, 2025 and 2024, respectively. Reconciliation of GAAP Net Income to Non-GAAP Net Income(Unaudited, in thousands except per share amounts)   Three Months Ended  June 30, 2025     Pre-Tax    Tax Impact    After-Tax    Per Share ImpactGAAP net income $43,379  $(10,798) $32,581  $0.54              Non-GAAP adjustments:                Cost of Sales                Amortization of intangibles  18,980   (4,485)  14,495   0.24 Inventory mark-up related to acquisitions  67   (16)  51   0.00 Operating Expenses              Contingent consideration expense  143   25   168   0.00 Amortization of intangibles  2,543   (601)  1,942   0.03 Performance-based share-based compensation (a)  5,879   (345)  5,534   0.09 Corporate restructuring (b)  2,587   (611)  1,976   0.03 Acquisition-related  2,140   (14)  2,126   0.04 Medical Device Regulation expenses (c)  1,634   (385)  1,249   0.02 Other (d)  50   (12)  38   0.00 Other (Income) Expense            Amortization of long-term debt issuance costs  1,414   (334)  1,080   0.02 Gain on disposal of business unit  (249)  —   (249)  (0.00)             Non-GAAP net income $78,567  $(17,576) $60,991  $1.01              Diluted shares              60,611                  Three Months Ended  June 30, 2024  Pre-Tax Tax Impact After-Tax Per Share ImpactGAAP net income    $45,843     $(10,117)    $35,726     $0.61              Non-GAAP adjustments:                Cost of Sales                Amortization of intangibles  13,126   (3,104)  10,022   0.17 Operating Expenses              Contingent consideration expense  306   (72)  234   0.00 Amortization of intangibles  1,744   (413)  1,331   0.02 Performance-based share-based compensation (a)  3,532   (563)  2,969   0.05 Corporate restructuring (b)  (54)  13   (41)  (0.00)Acquisition-related  1,221   (288)  933   0.02 Medical Device Regulation expenses (c)  1,930   (456)  1,474   0.03 Other (d)  55   (12)  43   0.00 Other (Income) Expense             Amortization of long-term debt issuance costs  1,477   (349)  1,128   0.02              Non-GAAP net income $69,180  $(15,361) $53,819  $0.92              Diluted shares              58,740                ______________________________ Note: Certain per-share impacts may not sum to totals due to rounding. Reconciliation of GAAP Net Income to Non-GAAP Net Income(Unaudited, in thousands except per share amounts)                Six Months Ended  June 30, 2025     Pre-Tax    Tax Impact    After-Tax    Per Share ImpactGAAP net income $81,337  $(18,609) $62,728  $1.03              Non-GAAP adjustments:                Cost of Sales               Amortization of intangibles  36,586   (8,645)  27,941   0.46 Inventory mark-up related to acquisitions  67   (16)  51   0.00 Operating Expenses              Contingent consideration expense  1,166   34   1,200   0.02 Amortization of intangibles  4,937   (1,167)  3,770   0.06 Performance-based share-based compensation (a)  10,653   (931)  9,722   0.16 Corporate restructuring (b)  2,587   (611)  1,976   0.03 Acquisition-related  2,156   (18)  2,138   0.04 Medical Device Regulation expenses (c)  3,228   (762)  2,466   0.04 Other (d)  29   (7)  22   0.00 Other (Income) Expense            Amortization of long-term debt issuance costs  2,828   (668)  2,160   0.04 Gain on disposal of business unit  (249)  —   (249)  (0.00)             Non-GAAP net income $145,325  $(31,400) $113,925  $1.87              Diluted shares             60,945                  Six Months Ended  June 30, 2024     Pre-Tax    Tax Impact    After-Tax    Per Share ImpactGAAP net income $80,191  $(16,225) $63,966  $1.09              Non-GAAP adjustments:                Cost of Sales                Amortization of intangibles  25,931   (6,132)  19,799   0.34 Operating Expenses             Contingent consideration expense  189   (25)  164   0.00 Amortization of intangibles  3,508   (830)  2,678   0.05 Performance-based share-based compensation (a)  5,660   (857)  4,803   0.08 Corporate restructuring (b)  (54)  13   (41)  (0.00)Acquisition-related  1,259   (297)  962   0.02 Medical Device Regulation expenses (c)  4,137   (977)  3,160   0.05 Other (d)  177   (42)  135   0.00 Other (Income) Expense             Amortization of long-term debt issuance costs  2,954   (697)  2,257   0.04              Non-GAAP net income $123,952  $(26,069) $97,883  $1.67              Diluted shares             58,653  ______________________________ Note: Certain per-share impacts may not sum to totals due to rounding. Reconciliation of Reported Operating Income to Non-GAAP Operating Income(Unaudited, in thousands except percentages)   Three Months Ended Three Months Ended Six Months Ended Six Months Ended  June 30, 2025 June 30, 2024 June 30, 2025 June 30, 2024     Amounts    % Sales    Amounts    % Sales    Amounts    % Sales    Amounts    % SalesNet Sales as Reported $382,462    $338,003     $737,813    $661,511                             GAAP Operating Income  46,880 12.3%  45,946  13.6 %  87,913 11.9%  81,868  12.4 %Cost of Sales                        Amortization of intangibles  18,980 5.0%  13,126  3.9 %  36,586 5.0%  25,931  3.9 %Inventory mark-up related to acquisitions  67 0.0%  —  —    67 0.0%  —  —  Operating Expenses                        Contingent consideration expense  143 0.0%  306  0.1 %  1,166 0.2%  189  0.0 %Amortization of intangibles  2,543 0.7%  1,744  0.5 %  4,937 0.7%  3,508  0.5 %Performance-based share-based compensation (a)  5,879 1.5%  3,532  1.0 %  10,653 1.4%  5,660  0.9 %Corporate restructuring (b)  2,587 0.7%  (54) (0.0)%  2,587 0.4%  (54) (0.0)%Acquisition-related  2,140 0.6%  1,221  0.4 %  2,156 0.3%  1,259  0.2 %Medical Device Regulation expenses (c)  1,634 0.4%  1,930  0.6 %  3,228 0.4%  4,137  0.6 %Other (d)  50 0.0%  55  0.0 %  29 0.0%  177  0.0 %                         Non-GAAP Operating Income $80,903 21.2% $67,806  20.1 % $149,322 20.2% $122,675  18.5 % ______________________________ Note: Certain percentages may not sum to totals due to rounding. (a) Represents performance-based share-based compensation expense, including stock-settled and cash-settled awards. (b) Includes employee termination benefits associated with activities related to corporate restructuring initiatives and costs to terminate certain distribution contracts from our Biolife acquisition. (c) Represents incremental expenses incurred to comply with the E.U. Medical Device Regulation. (d) Represents costs to comply with Merit’s corporate integrity agreement with the U.S. Department of Justice (the “DOJ”). Reconciliation of Reported Revenue to Constant Currency Revenue (Non-GAAP), and Constant Currency Revenue, Organic (Non-GAAP)(Unaudited, in thousands except percentages)                      Three Months Ended   Six Months Ended    June 30,    June 30,      % Change    2025     2024    % Change    2025     2024Reported Revenue 13.2%  $382,462  $338,003 11.5%  $737,813  $661,511                 Add: Impact of foreign exchange    (2,257)  —    1,148   —                 Constant Currency Revenue (a) 12.5%  $380,205  $338,003 11.7%  $738,961  $661,511                 Less: Revenue from certain acquisitions    (19,625)  —    (35,414)  —                 Constant Currency Revenue, Organic (a) 6.7%  $360,580  $338,003 6.4%  $703,547  $661,511 ______________________________ (a) A non-GAAP financial measure. For a definition of this and other non-GAAP financial measures, see the section of this release entitled “Non-GAAP Financial Measures.” Reconciliation of Reported Gross Margin to Non-GAAP Gross Margin (Non-GAAP)(Unaudited, as a percentage of reported revenue)                Three Months Ended Six Months Ended  June 30,  June 30,      2025 2024 2025 2024Reported Gross Margin 48.2%   47.7%   48.3%   47.3%             Add back impact of:                Amortization of intangibles 5.0%   3.9%   5.0%   3.9%Inventory mark-up related to acquisitions 0.0%   —% 0.0%   —%             Non-GAAP Gross Margin 53.2%   51.5%   53.3%   51.2%   ______________________________Note: Certain percentages may not sum to totals due to rounding.    ABOUT MERIT Founded in 1987, Merit is engaged in the development, manufacture, and distribution of proprietary medical devices used in interventional, diagnostic, and therapeutic procedures, particularly in cardiology, radiology, oncology, critical care, and endoscopy. Merit serves customers worldwide with a domestic and international sales force and clinical support team totaling more than 800 individuals. Merit employs approximately 7,300 people worldwide. CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING STATEMENTS This release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements include, among others: statements proceeded or followed by, or that include the words, “may,” “will,” “should,” “expects,” “plans,” “anticipates,” “intends,” “seeks,” “believes,” “estimates,” “projects,” “forecasts,” “potential,” “target,” “continue,” “upcoming,” “optimistic” or other forms of these words or similar words or expressions, or the negative thereof or other comparable terminology;statements that address Merit’s future operating performance or events or developments that Merit’s management expects or anticipates will occur, including, without limitation, any statements regarding Merit’s projected revenues, earnings or other financial measures, Merit’s plans and objectives for future operations, Merit’s proposed new products or services, the integration, development or commercialization of the business or any assets acquired from other parties, future economic conditions or performance, the implementation of, and results which may be achieved through, Merit’s Continued Growth Initiatives Program or other business optimization initiatives, and any statements of assumptions underlying any of the foregoing; andstatements regarding Merit’s past performance, efforts, or results about which inferences or assumptions may be made, including statements proceeded or followed by the words “preliminary,” “initial,” “potential,” “possible,” “diligence,” “industry-leading,” “compliant,” “indications,” or “early feedback” or other forms of these words or similar words or expressions, or the negative thereof or other comparable terminology. The forward-looking statements contained in this release are based on Merit management’s current expectations and assumptions regarding future events or outcomes. If underlying expectations or assumptions prove inaccurate, or risks or uncertainties materialize, actual results will likely differ, and could differ materially, from Merit’s expectations reflected in any forward-looking statements. Financial estimates are subject to change and are not intended to be relied upon as predictions of future operating results. Investors are cautioned not to unduly rely on any such forward-looking statements. The following are some of the important risks and uncertainties that could cause Merit’s actual results to differ from Merit’s expectations in any forward-looking statements: inherent risks and uncertainties associated with consequences of Merit’s executive succession planning activities and leadership transition; risks and uncertainties regarding trade policies or related actions implemented by the U.S. or other countries, including existing, proposed or prospective tariffs, duties or other measures; inherent risks and uncertainties associated with Merit’s acquisition of Biolife in May 2025; Merit’s integration of the Biolife business and operations and its ability to achieve revenues and other financial measures consistent with its forecasts projected for the Biolife acquisition; inherent risks and uncertainties associated with Merit’s integration of the business and products acquired from Cook Medical in November 2024 and Merit’s ability to achieve anticipated financial results, product development and other anticipated benefits of such acquisition; effects of the Convertible Notes on Merit’s net income and earnings per share performance; disruptions in Merit’s supply chain, manufacturing or sterilization processes; U.S. and global political, economic, competitive, reimbursement and regulatory conditions; reduced availability of, and price increases associated with, components and other raw materials; increases in transportation expenses; risks relating to Merit’s potential inability to successfully manage growth through acquisitions generally, including the inability to effectively integrate acquired operations or products or commercialize technology developed internally or acquired through completed, proposed or future transactions; fluctuations in interest or foreign currency exchange rates and inflation; risks and uncertainties associated with Merit’s information technology systems, including the potential for breaches of security and evolving regulations regarding privacy and data protection; governmental scrutiny and regulation of the medical device industry, including governmental inquiries, investigations and proceedings involving Merit; difficulties relating to development, testing and regulatory approval, clearance and maintenance of Merit’s products; the safety, efficacy and patient and physician adoption of Merit’s products; uncertainties regarding enrollment and outcomes of ongoing and future clinical trials and market studies relating to Merit’s products; modification or limitation of, or policies and procedures associated with, governmental or private insurance reimbursement policies; litigation and other judicial proceedings affecting Merit; the potential of fines, penalties or other adverse consequences if Merit’s employees or agents violate the U.S Foreign Corrupt Practices Act or other laws or regulations; consequences associated with a Corporate Integrity Agreement executed between Merit and the DOJ; restrictions on Merit’s liquidity or business operations resulting from its debt agreements; infringement of Merit’s technology or the assertion that Merit’s technology infringes the rights of other parties; product recalls and product liability claims; potential for significant adverse changes in governing regulations; changes in tax laws and regulations in the United States or other jurisdictions or exposure to additional tax liabilities which may adversely affect Merit’s effective tax rate; termination of relationships with Merit’s suppliers, or failure of such suppliers to perform; development of new products and technology that could render Merit’s existing or future products obsolete; market acceptance of new products; dependence on distributors to commercialize Merit’s products in various jurisdictions outside the U.S.; failure to comply with applicable environmental laws; changes in key personnel; labor shortages and increases in labor costs; price and product competition; extreme weather events; and geopolitical events. For a further discussion of the risks and uncertainties which may affect Merit’s business, operations and financial condition, see Part I, Item 1A, “Risk Factors” in Merit’s Annual Report on Form 10-K for the year ended December 31, 2024 filed with the SEC, Part II, Item 1A, “Risk Factors” in Merit’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2025 filed with the SEC and Merit’s other filings with the SEC. All subsequent forward-looking statements attributable to Merit or persons acting on its behalf are expressly qualified in their entirety by these cautionary statements. Actual results will likely differ, and may differ materially, from anticipated results. Financial estimates are subject to change and are not intended to be relied upon as predictions of future operating results. Those estimates and all other forward-looking statements included in this release are made only as of the date of this release, and except as otherwise required by applicable law, Merit assumes no obligation to update or disclose revisions to estimates and all other forward-looking statements. TRADEMARKS Unless noted otherwise, trademarks and registered trademarks used in this release are the property of Merit Medical Systems, Inc., its subsidiaries, or its licensors.  Contacts:   PR/Media Inquiries:Investor Inquiries:  Sarah ComstockMike Piccinino, CFA, IRC  Merit MedicalICR Healthcare  +1-801-432-2864+1-443-213-0509  sarah.comstock@merit.commike.piccinino@icrhealthcare.com     

HeartSciences Provides Business Update and Reports Fiscal 2025 Financial Results

Southlake, TX, July 24, 2025 (GLOBE NEWSWIRE) — HeartSciences Inc. (Nasdaq: HSCS; HSCSW) (“HeartSciences” or the “Company”), an artificial intelligence (“AI”)-powered medical technology company transforming ECGs/EKGs to enable earlier detection of heart disease, today announced its financial results for the fiscal year ended April 30, 2025, and provided a business update highlighting significant strategic progress.

Stereotaxis Announces $12.5 Million Registered Direct Offering of Common Stock

ST. LOUIS, July 17, 2025 (GLOBE NEWSWIRE) — Stereotaxis, Inc. (NYSE: STXS), a pioneer and global leader in surgical robotics for minimally invasive endovascular intervention, today announced it has entered into definitive agreements with investors for the sale of approximately $12.5 million of its shares of common stock in a registered direct offering, at a price per share of $2.00. The financing is being led by a strategic industry partner along with participation from a select group of institutional investors.

Kestra Medical Technologies Reports Fourth Quarter and Fiscal Year 2025 Financial Results

KIRKLAND, Wash., July 15, 2025 (GLOBE NEWSWIRE) — Kestra Medical Technologies, Ltd. (Nasdaq: KMTS), a wearable medical device and digital healthcare company, today reported financial results for the fourth quarter and fiscal year ended April 30, 2025. Financial Highlights Reported revenue of $17.2 million in Q4 FY25, an increase of 71% compared to the prior year period.Reported revenue of $59.8 million in FY25, an increase of 115% compared to FY24.Generated gross margin of 44.3% in Q4 FY25 compared to 13.9% in the prior year period.Generated gross margin of 40.5% in FY25 compared to 1.3% in FY24.Initiated FY26 revenue guidance of $85 million, an increase of 42% compared to FY25. “We capped an exciting year for Kestra with a very strong finish to our fiscal 2025. This quarter’s financial results reflect accelerating demand for our best-in-class cardiac recovery system as we continue to benefit from heightened prescriber awareness and the overwhelmingly positive experience patients are having with the ASSURE® system,” said Brian Webster, President and CEO. “In addition to our commercial execution, we are encouraged by the meaningful improvement in our gross margin, a result of the attractive unit economics and positive leverage inherent in our business model.” Mr. Webster continued, “In fiscal year 2025, the ASSURE® system protected thousands of patients from sudden cardiac arrest, a testament to the dedication of our mission-driven team. We also made progress on several key operational objectives, including significant growth of our commercial organization and planned enhancements to our revenue cycle capabilities. We remain confident that our commitment to innovation and intense focus on prescriber and patient support will drive market expansion and advance Kestra’s pursuit of market leadership.” Fourth Quarter Fiscal 2025 Financial Results Total revenue was $17.2 million in Q4, an increase of 71% compared to the prior year period. 3,903 prescriptions were written for the ASSURE® system in Q4, an increase of 43% compared to the prior year period.Revenue growth was driven by a higher share of wallet with existing customers and activation of new accounts. Revenue also benefited from a higher mix of in-network patients and improvements in revenue cycle management capabilities. Gross profit was $7.6 million in Q4 compared to $1.4 million in the prior year period. Gross margin expanded to 44.3% in Q4 compared to 13.9% in the prior year period, driven by volume leverage and a higher mix of in-network patients. GAAP operating expenses were $55.8 million in Q4 and included $22.3 million of share-based compensation expense and $3.8 million of professional services expenses related to the company’s IPO. GAAP operating expenses were $21.7 million in the prior year period. As a result of the company’s IPO in March, share-based compensation expense in Q4 included one-time impacts from the accelerated vesting of incentive units and the issuance of stock options to Kestra team members.Excluding share-based compensation and professional services expenses related to the IPO, operating expenses were $29.7 million in Q4 compared to $21.4 million in the prior year period. The increase was attributable to growth in expenses related to commercial and revenue cycle resources. GAAP net loss and comprehensive loss was $51.1 million in Q4 compared to GAAP net loss and comprehensive loss of $22.3 million in the prior year period. Adjusted EBITDA* loss was $20.3 million in Q4 compared to an adjusted EBITDA loss of $16.5 million in the prior year period. Cash and cash equivalents totaled $237.6 million as of April 30, 2025. Fiscal Year 2025 Financial Results Total revenue was $59.8 million in FY25, an increase of 115% compared to FY24. 13,193 prescriptions were written for the ASSURE® system in FY25, an increase of 72% compared to FY24. Gross profit was $24.2 million in FY25 compared to $0.4 million in FY24. Gross margin expanded to 40.5% in FY25 compared to 1.3% in FY24. GAAP operating expenses were $130.6 million in FY25 compared to $85.4 million in FY24. Excluding share-based compensation and professional services expenses related to the IPO, operating expenses were $100.6 million in FY25 compared to $83.9 million in FY24. GAAP net loss and comprehensive loss was $113.8 million in FY25 compared to GAAP net loss and comprehensive loss of $94.1 million in FY24. Adjusted EBITDA* loss was $68.4 million in FY25 compared to an Adjusted EBITDA loss of $72.0 million in FY24. *Adjusted EBITDA is a non-GAAP financial measure. See “Use of Non-GAAP Financial Measures” below for additional information. A reconciliation of Adjusted EBITDA to the most directly comparable GAAP measure is included in this press release. Fiscal Year 2026 Revenue GuidanceKestra expects revenue of $85 million in FY26, an increase of 42% compared to FY25. Webcast and Conference CallKestra will host a conference call today at 4:30 p.m. ET to discuss fourth quarter and fiscal year 2025 financial results. A live and archived webcast of the event will be available in the “Events” section of the investor relations website. Use of Non-GAAP Financial MeasuresThis press release contains certain financial information that is not presented in conformity with U.S. generally accepted accounting principles (“GAAP”), including Adjusted EBITDA. The non-GAAP financial measures are provided as supplemental information to Kestra’s financial measures presented in this press release that are calculated and presented in accordance with GAAP. Adjusted EBITDA, which is calculated as net income (loss), as adjusted to exclude other income/expense (including interest), income tax expense (benefit), depreciation and amortization expense, share-based compensation expense, and expenses related to Kestra’s initial public offering, is presented because management believes it allows investors to view the Company’s performance in a manner similar to the method used by management to evaluate the Company’s performance for both strategic and annual operating planning. Management believes that in order to properly understand short-term and long-term financial trends, it is helpful for investors to understand the impact of the items excluded from the calculation of Adjusted EBITDA, in addition to considering the Company’s GAAP financial measures. The excluded items vary in frequency and/or impact on our results of operations and management believes that the excluded items are not reflective of our ongoing core business operations and financial condition. Excluding such items allows investors and analysts to compare our operating performance to other companies in our industry and to compare our period-over-period results. The non-GAAP financial measures used by Kestra may not be the same or calculated in the same manner as those used and calculated by other companies. Non-GAAP financial measures have limitations as analytical tools and should not be considered in isolation or as a substitute for Kestra’s financial results prepared and reported in accordance with GAAP. We urge investors to review the reconciliation of these non-GAAP financial measures to the comparable GAAP financial measures included in this press release, and not to rely on any single financial measure to evaluate our business. A reconciliation of Adjusted EBITDA reported in this press release to the most comparable GAAP measure for the respective periods appears in the table captioned “Reconciliation of GAAP Net Income (Loss) to Adjusted EBITDA” later in this release. Within the accompanying financial tables presented, certain columns and rows may not add due to the use of rounded numbers. Forward-Looking StatementsExcept where otherwise noted, the information contained in this press release is as of July 15, 2025. Statements in this press release and on the related teleconference that express a belief, expectation or intention, as well as those that are not historical fact, are forward-looking statements. Except as required by law, the Company undertakes no obligation to publicly update any forward-looking statements, whether as a result of new information, future events or otherwise. This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements about, among other topics, our anticipated operating and financial performance, including financial guidance and projections; business plans, strategy, goals and prospects; and expectations for our products. Given their forward-looking nature, these statements involve substantial risks, uncertainties and potentially inaccurate assumptions, and we cannot ensure that any outcome expressed in these forward-looking statements will be realized in whole or in part. You can identify these statements by the fact that they use future dates or use words such as “will,” “may,” “could,” “likely,” “ongoing,” “anticipate,” “estimate,” “expect,” “project,” “intend,” “plan,” “believe,” “assume,” “target,” “forecast,” “guidance,” “goal,” “objective,” “aim,” “seek,” “potential,” “hope” and other words and terms of similar meaning. Kestra’s financial guidance is based on estimates and assumptions that are subject to significant uncertainties. Among the factors that could cause actual results to differ materially from past results and future plans and projected future results are the following: risks related to our limited operating history and history of net losses; our ability to successfully achieve substantial market adoption of our products; competitive pressures; our ability to adapt our manufacturing and production capacities to evolving patterns of demand, governmental actions and customer trends; product defects or complaints and related liability; our ability to obtain and maintain adequate coverage and reimbursement levels for our products; our ability to comply with changing laws and regulatory requirements and resulting costs; our dependence on a limited number of suppliers; and other risks and uncertainties, including those described under the heading “Risk Factors” in our Registration Statement on Form S-1 and other filings filed or to be filed with the U.S. Securities and Exchange Commission (“SEC”), including our Annual Report on Form 10-K for the fiscal year ended April 30, 2025. These filings, when made, are available on the Investor Relations section of our website at https://investors.kestramedical.com/ and on the SEC’s website at https://sec.gov/. About KestraKestra Medical Technologies, Ltd. is a commercial-stage wearable medical device and digital healthcare company focused on transforming patient outcomes in cardiovascular disease using monitoring and therapeutic intervention technologies that are intuitive, intelligent, and connected. For more information, visit www.kestramedical.com. KESTRA MEDICAL TECHNOLOGIES, LTD. AND SUBSIDIARIESCONSOLIDATED BALANCE SHEETS (in thousands, except share and per share amounts)(unaudited)  April 30,  2025  2024       Assets     Current assets     Cash and cash equivalents$237,595  $8,249 Accounts receivable, net 8,081   1,998 Disposable medical equipment supplies 6,572   3,290 Prepaid expenses and other current assets 3,080   1,370 Total current assets 255,328   14,907       Right-of-use assets 2,078   2,286 Deposits 2,021   1,710 Restricted cash 334   334 Property and equipment, net 34,830   26,105 Other long-term assets 1,153   607 Total assets$295,744  $45,949       Liabilities, Redeemable Preferred Stock and Shareholders’ Equity (Deficit)     Current liabilities     Accounts payable$23,961  $23,892 Accrued liabilities 13,829   9,079 Operating lease liabilities, current portion 187   — Total current liabilities 37,977   32,971       Operating lease liabilities, net of current portion 3,026   2,633 Warrant liabilities 8,097   — Other long-term liabilities 140   76 Long-term debt, net 41,098   42,536 Total liabilities 90,338   78,216       Commitments and contingencies           Redeemable preferred stock, $0.01 par value; 0 and 5,000,000 shares authorized as of April 30, 2025 and April 30, 2024, respectively; 0 and 177,110 shares issued and outstanding as of April 30, 2025 and April 30, 2024, respectively —   177,110       Shareholders’ equity (deficit)           Common stock, $0.01 par value; 5,000,000 shares authorized as of April 30, 2024; 105,808 shares issued and outstanding as of April 30, 2024 —   1 Common shares, $1.00 par value; 100,000,000 shares authorized as of April 30, 2025; 51,348,656 shares issued and outstanding as of April 30, 2025 51,349   — Additional paid-in capital 674,306   197,057 Accumulated deficit (520,249)  (406,435)Total shareholders’ equity (deficit) 205,406   (209,377)Total liabilities and shareholders’ equity (deficit)$295,744  $45,949  KESTRA MEDICAL TECHNOLOGIES, LTD. AND SUBSIDIARIESCONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (in thousands, except share and per share amounts)(unaudited)  Three Months Ended April 30,  Year Ended April 30,  2025  2024  2025  2024             Revenue$17,233  $10,054  $59,815  $27,814 Cost of revenue 9,600   8,657   35,605   27,452 Gross profit 7,633   1,397   24,210   362 Operating expenses:           Research and development 5,386   3,821   15,652   15,490 Selling, general and administrative 50,459   17,925   114,936   69,935 Total operating expenses 55,845   21,746   130,588   85,425 Loss from operations (48,212)  (20,349)  (106,378)  (85,063)Other expense (income):           Interest expense 1,760   1,935   7,734   6,230 Interest income (1,656)  —   (3,199)  — Other expense 2,693   27   2,766   2,803 Net loss before provision for income taxes (51,009)  (22,311)  (113,679)  (94,096)Provision for income taxes 102   (27)  135   24 Net loss and comprehensive loss (51,111)  (22,284)  (113,814)  (94,120)Less: Undeclared preferred stock dividends 3,291   1,994   12,321   6,721 Net loss attributable to common shareholders, basic and diluted$(54,402) $(24,278) $(126,135) $(100,841)            Net loss per share attributable to common shareholders, basic and diluted$(2.21) $(1.22) $(5.13) $(5.07)Weighted-average shares of common shares outstanding, basic and diluted 24,583,745   19,885,382   24,583,745   19,885,382  RECONCILIATION OF GAAP NET LOSS AND COMPREHENSIVE LOSS TO ADJUSTED EBITDA (in thousands)(unaudited)  Three Months Ended April 30,  Year Ended April 30,  2025  2024  2025  2024             GAAP Net loss and comprehensive loss$(51,111) $(22,284) $(113,814) $(94,120)Non-GAAP Adjustments:           Interest expense 1,760   1,935   7,734   6,230 Interest income (1,656)  —   (3,199)  — Other expense 2,693   27   2,766   2,803 Provision for income taxes 102   (27)  135   24 Depreciation expense 1,836   3,502   7,968   11,560 Share-based compensation expense 22,313   389   24,271   1,488 IPO expense 3,809   —   5,736   — Adjusted EBITDA$(20,254) $(16,458) $(68,403) $(72,015) CONTACT: Investor contact
Neil Bhalodkar
neil.bhalodkar@kestramedical.com

Argon Medical Streamlines Distribution of Product and Enhances Customer Training for Europe, Asia, and Africa with the Debut of a Modern, Mixed-Use Facility

PLANO, Texas, July 15, 2025 /PRNewswire/ — Argon Medical, a leading provider of medical device solutions for Interventional Radiology, Vascular Surgery, Interventional Cardiology, and Oncology procedures, announces the grand opening of its new Distribution & Education Center (ADEC),…