Data demonstrates MFI’s propriety software enables 15 minute immediate back-to-back Rest-
Stress scanning with Flyrcadoä radiotracer
SOUTH OGDEN, UT – June 20, 2025 –- MultiFunctional Imaging LLC (MFI) today announced the publication
of data submitted to the Journal of Nuclear Cardiology (JNC), a leading peer-reviewed journal. The study
validates MFI’s proprietary mfiVerseä software enabling rapid, 15 minute back-to-back Rest-Stress scan
protocols with the recently FDA-approved Flyrcadoä radiotracer.
The publication, titled “Technical Evaluation of Immediate Back-to-Back Rest-Stress PET Scanning with F18
Flurpiridaz” and coauthored by physicians from the Mayo Clinic and Massachusetts General Hospital,
demonstrates that rest and stress Flyrcado PET images can be obtained immediately back-to-back without
rest-stress delay when accurate correction for residual activity is performed. This rapid scanning protocol
raises the standard of patient care by enabling greater throughput of rest/pharmacologic stress procedures.
“The ability to image both rest and stress in a single, 15-20 minute procedure addresses the throughput
challenges of imaging with Flurpiridaz, greatly reducing total procedure time and improving the patient
experience,” states co-author Dr. Panithaya Chareonthaitawee, Director, Nuclear Cardiology Laboratory at
Mayo Clinic and current president of the American Society of Nuclear Cardiology (ASNC). “Larger scale
studies and real world experience are warranted to determine the full benefit of the approach.”
Myocardial perfusion imaging (also referred to as Rest-Stress) is a nuclear medicine procedure that
illustrates the function of the heart muscle. It is widely used to evaluate patients with known or suspected
heart disease and can identify ischemia, infarct, and heart wall motion abnormalities. In the United States,
approximately 10 million people each year undergo a myocardial perfusion exam.
Commenting on the fast scanning approach, co-author Dr. Bradley Kemp, Medical Physicist at Mayo Clinic,
adds “We’ve been using mfiVerse for several years with N13 Ammonia. The techs love the back-to-back
protocol, and we’re excited to achieve the same speed and throughput with F18 Flurpiridaz.”
About MultiFunctional Imaging
MultiFunctional Imaging LLC is a medical device company dedicated to the development of patented
technologies for single-scan myocardial perfusion imaging, single-scan multi-tracer cancer imaging for
quantification and assessment of tumor function, and tools for multi-tracer PET research and kinetic
modeling. The mfiVerseä clinical software has 510(k) clearance for rest-stress cardiac imaging, and MFI’s
mfEVolveä research software is available for multi-tracer and kinetic modeling research. MultiFunctional
Imaging LLC was created in 2014 as a spin-out from the University of Utah. For more information, please
visit www.MultiFunctionalImaging.com.
About Journal of Nuclear Cardiology
As the official publication of the American Society of Nuclear Cardiology (ASNC), the Journal of Nuclear
Cardiology brings readers peer-reviewed original articles and timely discussions about the current and
future roles of nuclear cardiology and other imaging modalities. For more information, please visit
www.JournalofNuclearCardiology.org
Contact:
Dave Dolan, Executive Chairman
Dave.Dolan@MFImage.com
