Financial

Merck Foundation Launches $22 Million Initiative to Improve Cardiovascular Care in the U.S.

Building on the Merck Foundation’s longstanding commitment to advancing access to high-quality health care, new national initiative supports grants to 11 organizations across the country RAHWAY, N.J.–(BUSINESS WIRE)–The Merck Foundation announced today the launch of the Collaborative for Equity in Cardiac Care, a $22 million, five-year initiative aimed at enhancing […]

Orchestra BioMed to Host Business Update Call on November 12, 2025

NEW HOPE, Pa., Nov. 03, 2025 (GLOBE NEWSWIRE) — Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patients through strategic partnerships with market-leading global medical device companies, today announced that company management will host a business update call on Wednesday, November 12th at 8:00 AM ET. The business update will focus on recent significant clinical, strategic and financing developments, including the Company’s additional strategic investment from and collaboration expansion with Medtronic, its new strategic capital relationship with Ligand, its new right of first refusal agreement with Terumo, acceleration of enrollment in the BACKBEAT pivotal study of AVIM Therapy, the initiation of patient enrollment in the Virtue SAB US pivotal IDE coronary trial. Conference Call DetailsWednesday, November 12, at 8:00 AM Eastern Time Toll Free: 877-407-9039International: 201-689-8470Conference ID: 13756518Webcast: https://viavid.webcasts.com/starthere.jsp?ei=1738644&tp_key=c80bc7995c About Orchestra BioMed Orchestra BioMed is a biomedical innovation company accelerating high-impact technologies to patients through strategic collaborations with market-leading global medical device companies. The Company’s two flagship product candidates – Atrioventricular Interval Modulation (AVIM) Therapy and Virtue® Sirolimus AngioInfusion™ Balloon (Virtue SAB) – are currently undergoing pivotal clinical trials for their lead indications, each representing multi-billion-dollar annual global market opportunities. AVIM Therapy is a bioelectronic treatment for hypertension, the leading risk factor for death worldwide, and is designed to be delivered as a firmware upgrade to a pacemaker and achieve immediate, substantial and sustained reductions in blood pressure in patients with hypertensive heart disease. The Company has a strategic collaboration with Medtronic (NYSE: MDT), one of the largest medical device companies in the world, for the development and commercialization of AVIM Therapy for the treatment of uncontrolled hypertension in pacemaker-indicated patients. AVIM Therapy has FDA Breakthrough Device Designation for these patients, as well as an estimated 7.7 million total patients in the U.S. with uncontrolled hypertension despite medical therapy and increased cardiovascular risk. Virtue SAB is a highly differentiated, first-of-its-kind drug delivery angioplasty balloon system designed to deliver a proprietary extended-release formulation of sirolimus, SirolimusEFR™, for the treatment of atherosclerotic artery disease, the leading cause of mortality worldwide. Virtue SAB has been granted Breakthrough Device Designation by the FDA for the treatment of coronary ISR, coronary small vessel disease and below-the-knee peripheral artery disease. For further information about Orchestra BioMed, please visit www.orchestrabiomed.com, and follow us on LinkedIn. Investor Contact:Silas NewcombOrchestra BioMedSnewcomb@orchestrabiomed.com Media Contact:Kelsey Kirk-EllisOrchestra BioMedkkirkellis@orchestrabiomed.com

InspireMD Names Peter A. Soukas, M.D., as Chief Medical Officer

MIAMI, Nov. 03, 2025 (GLOBE NEWSWIRE) — InspireMD, Inc. (Nasdaq: NSPR) (“InspireMD” or the “Company”), developer of the CGuard® Prime carotid stent system for the prevention of stroke, today announced the appointment of Peter A. Soukas, M.D., as Chief Medical Officer to advance its mission to deliver best-in-class tools for carotid intervention.

Conavi Expands Leadership Team to Support Next Phase of U.S. Commercialization

– Mark Quick Appointed Chief Financial Officer, Bringing Extensive Public Company Capital Markets Expertise — Current CFO, Stefano Picone, will take on a Transitional Strategic Role to Support Leadership Continuity During Growth Phase — Leadership additions follow submission of next-generation Novasight™ to the FDA for 510(k) clearance -TORONTO, Nov. 03, 2025 (GLOBE NEWSWIRE) — Conavi Medical  (TSXV: CNVI) (OTCQB: CNVIF) (“Conavi” or the “Company”), a commercial-stage medical device company focused on designing, manufacturing, and marketing imaging technologies to guide minimally invasive cardiovascular procedures, today announced strategic leadership changes aligned to the Company’s planned commercial launch and expansion in the United States.Conavi has submitted its next generation Novasight Hybrid IVUS/OCT intravascular imaging system to the U.S. Food and Drug Administration (FDA) for 510(k) clearance, and is actively building the infrastructure required to support a successful U.S. launch in the largest market for intravascular imaging globally.As part of these preparations, Conavi has appointed Mark Quick as Chief Financial Officer, bringing strong capital-markets expertise from senior roles at publicly traded life sciences and medtech companies. He will oversee financial strategy and investor engagement as Conavi prepares for launch in the United States.Stefano Picone will take on a transitional strategic role with the Company as the Chief Strategy Officer. Having successfully guided Conavi through its go-public transaction, first public equity financing, and organizational scale-up, Mr. Picone now shifts focus to strategic execution and ensuring continuity as the Company advances through this commercial scale-up period.“We are entering a very exciting chapter for Conavi as we prepare for broader U.S. adoption of our hybrid imaging platform,” said Thomas Looby, Chief Executive Officer of Conavi Medical. “Mark brings the ideal financial and strategic mindset to help guide our U.S. launch and expand our presence in the capital markets. Stefano’s leadership over the past decade has been instrumental in establishing the corporate foundation we stand on today, and we are grateful for his significant financial stewardship and continued support as we execute on Conavi’s long-term growth and value-creation strategy. With these leadership enhancements and U.S. expansion activities advancing, we are confident we have the right team, capabilities, and focus in place to deliver success in the United States and create long-term value for shareholders.”“Conavi has a differentiated and highly compelling technology platform,” said Mark Quick, Chief Financial Officer of Conavi Medical. “I’m excited to join at this stage of growth and look forward to working with the team to advance a strong financial, operational, and capital markets strategy as the Company prepares for commercialization.”Mark Quick — Chief Financial OfficerMr. Quick is a seasoned finance executive with more than 20 years of experience in the medical technology and life sciences sectors. Prior to joining Conavi, he held senior financial leadership roles with publicly traded companies on Nasdaq, where he led capital markets strategy, budgeting and forecasting, financial reporting, and corporate development initiatives. Earlier in his career, Mr. Quick served as a sell-side equity research analyst at Canaccord Genuity, where he covered the medical device industry. Mr. Quick holds a Bachelor of Science in Mechanical Engineering from the University of Massachusetts, Amherst, and an International Master of Business Administration from the University of South Carolina.About Conavi MedicalConavi Medical is focused on designing, manufacturing, and marketing imaging technologies to guide common minimally invasive cardiovascular procedures. Its patented Novasight Hybrid™ System is the first to combine intravascular ultrasound (IVUS) and optical coherence tomography (OCT) into a single device, enabling simultaneous and co-registered imaging of coronary arteries. The first-generation Novasight Hybrid™ System has regulatory clearance in the U.S., Canada, China, and Japan. For more information, visit conavi.com.Cautionary Statement Regarding Forward-Looking InformationThis news release contains “forward-looking statements” within the meaning of applicable Canadian and U.S. securities laws, which reflect the current expectations of management of Conavi’s future growth, results of operations, performance and business prospects and opportunities. Forward-looking statements are frequently, but not always, identified by words such as “may”, “would”, “could”, “will”, “anticipate”, “believe”, “plan”, “expect”, “intend”, “estimate”, “potential for” and similar expressions, although these words may not be present in all forward-looking statements. Forward-looking statements that appear in this release may include, without limitation, references to transitions in the Company’s strategic leadership, Conavi’s plans for the commercialization of its Novasight Hybrid™ System and expected FDA clearance and the commercial launch of next generation Novasight in the U.S. and other U.S. expansion activities.These forward-looking statements reflect management’s current beliefs with respect to future events, and are based on information currently available to management that, while considered reasonable by management as of the date on which the statements are made, are inherently subject to significant business, economic and competitive uncertainties and contingencies which could result in actions, events, conditions, results, performance or achievements to be materially different from those projected in the forward-looking statements. Forward-looking statements involve significant risks, uncertainties and assumptions and many factors could cause Conavi’s actual results, performance or achievements to be materially different from any future results, performance or achievements that may be expressed or implied by such forward-looking statements. Such factors and assumptions include, but are not limited to, Conavi’s ability to retain key personnel; its ability to execute on its business plans and strategies; and other factors listed in the “Risk Factors” sections of the joint information circular of Conavi dated August 30, 2024 and in the final short form prospectus of Conavi dated April 15, 2025 (each of which may be viewed at www.sedarplus.com). Should one or more of these risks or uncertainties materialize, or should assumptions underlying the forward-looking statements prove incorrect, actual results, performance, or achievements may vary materially from those expressed or implied by the forward-looking statements contained in this news release. These factors should be considered carefully, and prospective investors should not place undue reliance on the forward-looking statements.Although the forward-looking statements contained in the news release are based upon what management currently believes to be reasonable assumptions and Conavi has attempted to identify important factors that could cause actual actions, events, conditions, results, performance or achievements to differ materially from those described in forward-looking statements, Conavi cannot assure prospective investors that actual results, performance or achievements will be consistent with these forward-looking statements. Except as required by law, Conavi expressly disclaims any intention or obligation to update or revise any forward-looking statements whether as a result of new information, future events or otherwise. Accordingly, investors should not place undue reliance on forward-looking statements. All the forward-looking statements are expressly qualified by the foregoing cautionary statements.Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.Contact:Investors: Christina Cameron, IR@conavi.com

Merit Medical Reports Third Quarter 2025 Results and Updates Full-Year Guidance

Highlights† Reported revenue of $384.2 million, up 13.0%Constant currency revenue* and constant currency revenue, organic* up 12.5% and up 7.8%, respectivelyGAAP operating margin of 11.1%, compared to 11.0% in prior year periodNon-GAAP operating margin* of 19.7%, compared to 19.2% in prior year periodGAAP EPS $0.46, down 3.0%Non-GAAP EPS* $0.92, up 6.7%Free cash flow* generation of $141.6 million over first nine months of 2025, up 17.6% year-over-year † Comparisons above are calculated for the current quarter compared with the third quarter of 2024, unless otherwise specified. Amounts stated in this release are rounded, while percentages are calculated from the underlying amounts. * Constant currency revenue; constant currency revenue, organic; non-GAAP gross profit and margin; non-GAAP operating income and margin; non-GAAP net income; non-GAAP EPS; and free cash flow figures (used here and below) are non-GAAP financial measures. A reconciliation of these financial measures to their most directly comparable GAAP financial measures is included under the heading “Non-GAAP Financial Measures” below. SOUTH JORDAN, Utah, Oct. 30, 2025 (GLOBE NEWSWIRE) — Merit Medical Systems, Inc. (NASDAQ: MMSI), a leading global manufacturer and marketer of healthcare technology, today announced revenue of $384.2 million for the quarter ended September 30, 2025, an increase of 13.0% compared to the quarter ended September 30, 2024. Constant currency revenue for the third quarter of 2025 increased 12.5% compared to the prior year period and constant currency revenue, organic, for the third quarter of 2025 increased 7.8% compared to the prior year period. “Merit delivered better-than-expected financial performance in the third quarter, with top and bottom-line results exceeding the high-end of the company’s expectations,” said Martha G. Aronson, Merit’s President and CEO. “We have increased our 2025 revenue and non-GAAP earnings per share guidance to reflect the stronger-than-expected third quarter results and remain confident in our team’s ability to deliver strong execution, stable constant currency growth, improving profitability and solid cash flow generation this year.” Ms. Aronson continued: “I am proud to join the Merit Medical team and am committed to working closely with the executive leadership team, Fred and the rest of Merit’s Board of Directors to achieve a smooth transition and continued strong execution towards our Continued Growth Initiatives Program and related financial targets for the three-year period ending December 31, 2026.” Merit’s revenue by operating segment and product category for the three and nine-month periods ended September 30, 2025 and 2024 was as follows (unaudited; in thousands, except for percentages):                    Three Months Ended Reported    Constant Currency* September 30,    Impact of foreign September 30,    2025 2024(1) % Change exchange 2025 % ChangeCardiovascular                 Peripheral Intervention$144,781 $133,083 8.8% $(602) $144,179 8.3%Cardiac Intervention 116,682  90,240 29.3%  (719)  115,963 28.5%Custom Procedural Solutions 54,136  50,455 7.3%  (441)  53,695 6.4%OEM 50,826  49,077 3.6%  (150)  50,676 3.3%Total 366,425  322,855 13.5%  (1,912)  364,513 12.9%                  Endoscopy                 Endoscopy Devices 17,732  16,990 4.4%  (14)  17,718 4.3%                  Total$384,157 $339,845 13.0% $(1,926) $382,231 12.5%  Nine Months Ended Reported    Constant Currency * September 30,    Impact of foreign September 30,    2025 2024(1) % Change exchange 2025 % ChangeCardiovascular                 Peripheral Intervention$424,907 $397,535 6.9% $444  $425,351 7.0%Cardiac Intervention 331,674  273,723 21.2%  (330)  331,344 21.1%Custom Procedural Solutions 155,712  149,110 4.4%  (666)  155,046 4.0%OEM 156,870  143,676 9.2%  (221)  156,649 9.0%Total 1,069,163  964,044 10.9%  (773)  1,068,390 10.8%                  Endoscopy                 Endoscopy Devices 52,807  37,312 41.5%  (5)  52,802 41.5%                  Total$1,121,970 $1,001,356 12.0% $(778) $1,121,192 12.0% (1)Commencing January 1, 2025, we reorganized our sales teams and product categories to include revenues from the sale of our spine devices under our OEM product category. Revenue figures for 2024 have been recast to reflect this realignment of our portfolio of spine products, representing approximately $5.7 million and $16.7 million in revenue for the three and nine-month periods ended September 30, 2024, within the OEM product category to provide comparability between the reported periods. Merit’s GAAP gross margin for the third quarter of 2025 was 48.5%, compared to GAAP gross margin of 46.4% for the third quarter of 2024. Merit’s non-GAAP gross margin* for the third quarter of 2025 was 53.6%, compared to non-GAAP gross margin* of 50.9% for the third quarter of 2024. Merit’s GAAP net income for the third quarter of 2025 was $27.8 million, or $0.46 per share, compared to GAAP net income of $28.4 million, or $0.48 per share, for the third quarter of 2024. Merit’s non-GAAP net income* for the third quarter of 2025 was $54.9 million, or $0.92 per share, compared to non-GAAP net income* of $51.2 million, or $0.86 per share, for the third quarter of 2024. As of September 30, 2025, Merit had cash and cash equivalents of $392.5 million and total debt obligations of $747.5 million, compared to cash and cash equivalents of $376.7 million and total debt obligations of $747.5 million as of December 31, 2024. Merit had available borrowing capacity of approximately $697 million as of September 30, 2025. Fiscal Year 2025 Financial Guidance Based upon the information currently available to Merit’s management, for the year ending December 31, 2025, absent the potential impact of trade policies and related actions implemented by the U.S. and other countries subsequent to today’s date, material acquisitions, non-recurring transactions or other factors beyond Merit’s current expectations, Merit anticipates the following financial results: Revenue and Earnings Guidance*  Updated GuidancePrior Guidance(2)Financial MeasureYear Ending% ChangeYear Ending% Change December 31, 2025Y/YDecember 31, 2025Y/Y     Net Sales$1.502 – $1.515 billion11% – 12%$1.495 – $1.507 billion10% – 11%Cardiovascular Segment$1.430 – $1.441 billion10% – 11%$1.423 – $1.434 billion9% – 10%Endoscopy Segment$72.0 – $74.0 million32% – 34%$72.0 – $73.0 million32% – 34%     Non-GAAP    Earnings Per Share(1)$3.66 – $3.796% – 10%$3.52 – $3.722% – 8% *Percentage figures approximated; dollar figures may not foot due to rounding(1)Merit’s non-GAAP earnings per share reflect the dilutive impact of its 3.00% Convertible Senior Notes due 2029 (the “Convertible Notes”) calculated using the if-converted method of approximately $0.04 per share for the year ending December 31, 2025. Any offsetting impacts of the capped call associated with the Convertible Notes are not considered.(2)“Prior Guidance” reflects Merit’s full-year 2025 financial guidance, previously introduced on July 30, 2025. 2025 Net Sales Guidance – % Change from Prior Year (Constant Currency) Reconciliation*  Updated Guidance Prior Guidance(1) Low High Low High2025 Net Sales Guidance – % Change from Prior Year (GAAP)10.7% 11.7% 10.2% 11.1%Estimated impact of foreign currency exchange rate fluctuations(0.5%) (0.5%) (0.5%) (0.5%)2025 Net Sales Guidance – % Change from Prior Year (Constant Currency)10.3% 11.2% 9.7% 10.6% *Percentage figures approximated and may not foot due to rounding(1)“Prior Guidance” reflects Merit’s full-year 2025 financial guidance, previously introduced on July 30, 2025. Merit does not provide guidance for GAAP reported financial measures (other than revenue) or a reconciliation of forward-looking non-GAAP financial measures to the most directly comparable GAAP reported financial measures (other than revenue) because Merit is unable to predict with reasonable certainty the financial impact of various items which could impact Merit’s future financial results, such as expenses attributable to acquisitions or other extraordinary transactions, non-cash expenses related to amortization or write-off of previously acquired tangible and intangible assets, certain employee termination benefits, performance-based stock compensation expenses, expenses resulting from non-ordinary course litigation or administrative proceedings and resulting settlements, governmental proceedings, and changes in governmental or industry regulations. These items are uncertain, depend on various factors, and could have a material impact on GAAP reported results for the guidance period. For the same reasons, Merit is unable to address the significance of the unavailable information, which could be material to future results. Specifically, Merit is not, without unreasonable effort, able to reliably predict the impact of these items and Merit believes inclusion of a reconciliation of these forward-looking non-GAAP measures to their GAAP counterparts could be confusing to investors or cause undue reliance. Merit’s financial guidance for the year ending December 31, 2025 is subject to risks and uncertainties identified in this release and Merit’s filings with the U.S. Securities and Exchange Commission (the “SEC”). This guidance is based on information and estimates available to Merit as of October 30, 2025. Should known or unknown risks or uncertainties materialize or should underlying assumptions prove inaccurate, actual results will likely vary, and could vary materially, from past results and those anticipated, estimated or projected. CONFERENCE CALL Merit will hold its investor conference call today, Thursday, October 30, 2025, at 5:00 p.m., Eastern Time. To access the conference call, please pre-register using the following link. Registrants will receive confirmation with dial-in details. A live webcast and slide deck will also be available at merit.com. CONSOLIDATED BALANCE SHEETS(in thousands)       September 30,        2025 December 31,  (Unaudited) 2024ASSETS       Current Assets       Cash and cash equivalents$ 392,457  $ 376,715 Trade receivables, net  210,292    190,243 Other receivables  19,062    16,588 Inventories  326,550    306,063 Prepaid expenses and other assets  31,369    28,544 Prepaid income taxes  3,651    3,286 Income tax refund receivables  2,152    2,335 Total current assets  985,533    923,774       Property and equipment, net  418,004    386,165 Intangible assets, net  538,400    498,265 Goodwill  507,427    463,511 Deferred income tax assets  16,284    16,044 Operating lease right-of-use assets  88,496    65,508 Other assets  76,854    65,336 Total Assets$ 2,630,998  $ 2,418,603       LIABILITIES AND STOCKHOLDERS’ EQUITY       Current Liabilities       Trade payables$ 64,746  $ 68,502 Accrued expenses  147,377    134,077 Current operating lease liabilities  10,612    10,331 Income taxes payable  7,740    3,492 Total current liabilities  230,475    216,402       Long-term debt  732,916    729,551 Deferred income tax liabilities  26,707    240 Liabilities related to unrecognized tax benefits  2,169    2,118 Deferred compensation payable  17,083    19,197 Deferred credits  1,424    1,502 Long-term operating lease liabilities  77,624    54,783 Other long-term obligations  13,192    15,451 Total liabilities  1,101,590    1,039,244       Stockholders’ Equity       Common stock  747,103    703,219 Retained earnings  786,024    695,541 Accumulated other comprehensive loss  (3,719)   (19,401)Total stockholders’ equity  1,529,408    1,379,359 Total Liabilities and Stockholders’ Equity$ 2,630,998  $ 2,418,603  CONSOLIDATED STATEMENTS OF INCOME(Unaudited, in thousands except per share amounts)             Three Months Ended Nine Months Ended September 30, September 30, 2025 2024 2025 2024Net sales$384,157  $339,845  $1,121,970  $1,001,356 Cost of sales 197,746   182,310   579,052   531,006 Gross profit 186,411   157,535   542,918   470,350             Operating expenses:           Selling, general and administrative 119,801   99,644   340,384   288,657 Research and development 23,966   20,527   70,811   62,272 Contingent consideration expense 32   103   1,198   292 Total operating expenses 143,799   120,274   412,393   351,221             Income from operations 42,612   37,261   130,525   119,129             Other income (expense):           Interest income 3,615   6,652   11,166   21,489 Interest expense (6,754)  (7,501)  (20,097)  (23,226)Other income (expense) — net (933)  245   (1,717)  (544)Total other expense — net (4,072)  (604)  (10,648)  (2,281)            Income before income taxes 38,540   36,657   119,877   116,848             Income tax expense 10,785   8,213   29,394   24,438             Net income$27,755  $28,444  $90,483  $92,410             Earnings per common share           Basic$0.47  $0.49  $1.53  $1.59 Diluted$0.46  $0.48  $1.49  $1.57             Weighted average shares outstanding           Basic 59,245   58,231   59,095   58,110 Diluted 59,919   59,537   60,604   58,948  CONSOLIDATED STATEMENTS OF CASH FLOWS(Unaudited, in thousands)       Nine Months Ended  September 30,  2025     2024 CASH FLOWS FROM OPERATING ACTIVITIES:   Net income$ 90,483  $ 92,410 Adjustments to reconcile net income to net cash provided by operating activities:       Depreciation and amortization  91,629    74,093 Gain on disposition of a business  (249)   — Write-off of certain intangible assets and other long-term assets  152    401 Amortization of right-of-use operating lease assets  8,693    9,043 Fair value adjustments related to contingent consideration liabilities  1,198    292 Stock-based compensation expense  33,563    18,958 Other adjustments  4,711    4,569 Changes in operating assets and liabilities, net of acquisitions  (31,319)   (47,711)Total adjustments  108,378    59,645 Net cash, cash equivalents, and restricted cash provided by operating activities  198,861    152,055       CASH FLOWS FROM INVESTING ACTIVITIES:       Capital expenditures for property and equipment  (57,252)   (31,668)Cash paid for notes receivable and other investments  (14,936)   (10,223)Cash paid in acquisitions, net of cash acquired  (122,834)   (110,182)Other investing, net  (2,029)   (2,133)Net cash, cash equivalents, and restricted cash used in investing activities  (197,051)   (154,206)      CASH FLOWS FROM FINANCING ACTIVITIES:   Proceeds from issuance of common stock  22,179    15,424 Proceeds from (payments on) long-term debt  —    (76,063)Contingent payments related to acquisitions  (2,645)   (209)Payment of taxes related to an exchange of common stock  (8,597)   (1,592)Net cash, cash equivalents, and restricted cash provided by (used in) financing activities  10,937    (62,440)Effect of exchange rates on cash  3,047    724 Net increase (decrease) in cash, cash equivalents and restricted cash  15,794    (63,867)      CASH, CASH EQUIVALENTS AND RESTRICTED CASH:       Beginning of period  378,767    589,144 End of period$ 394,561  $ 525,277       RECONCILIATION OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH TO THE CONSOLIDATED BALANCE SHEETS:     Cash and cash equivalents  392,457    523,128 Restricted cash reported in prepaid expenses and other current assets  2,104    2,149 Total cash, cash equivalents and restricted cash$ 394,561  $ 525,277  Non-GAAP Financial Measures Although Merit’s financial statements are prepared in accordance with accounting principles generally accepted in the United States of America (“GAAP”), Merit’s management believes that the non-GAAP financial measures referenced in this release may provide investors with useful information regarding the underlying business trends and performance of Merit’s ongoing operations and can be useful for period-over-period comparisons of such operations. Non-GAAP financial measures used in this release include: constant currency revenue;constant currency revenue, organic;non-GAAP gross profit and margin;non-GAAP operating income and margin;non-GAAP net income;non-GAAP earnings per share; andfree cash flow. Merit’s management team uses these non-GAAP financial measures to evaluate Merit’s profitability and efficiency, to compare operating and financial results to prior periods, to evaluate changes in the results of its operating segments, and to measure and allocate financial resources internally. However, Merit’s management does not consider such non-GAAP measures in isolation or as an alternative to measures determined in accordance with GAAP. Readers should consider non-GAAP measures used in this release in addition to, not as a substitute for, financial reporting measures prepared in accordance with GAAP. These non-GAAP financial measures generally exclude some, but not all, items that may affect Merit’s net income. In addition, they are subject to inherent limitations as they reflect the exercise of judgment by management about which items are excluded. Merit believes it is useful to exclude such items in the calculation of non-GAAP gross profit and margin, non-GAAP operating income and margin, non-GAAP net income, and non-GAAP earnings per share (in each case, as further illustrated in the reconciliation tables below) because such amounts in any specific period may not directly correlate to the underlying performance of Merit’s business operations and can vary significantly between periods as a result of factors such as acquisition or other extraordinary transactions, non-cash expenses related to amortization or write-off of previously acquired tangible and intangible assets, certain employee termination benefits, expenses resulting from non-ordinary course litigation or administrative proceedings and resulting settlements, governmental proceedings or changes in tax or industry regulations, gains or losses on disposal of certain assets, equity method investment loss (income) from equity investees, and debt issuance costs. Merit may incur similar types of expenses in the future, and the non-GAAP financial information included in this release should not be viewed as a statement or indication that these types of expenses will not recur. Additionally, the non-GAAP financial measures used in this release may not be comparable with similarly titled measures of other companies. Merit urges readers to review the reconciliations of its non-GAAP financial measures to their most directly comparable GAAP financial measures included herein, and not to rely on any single financial measure to evaluate Merit’s business or results of operations. Constant Currency Revenue Merit’s constant currency revenue is prepared by converting the current-period reported revenue of subsidiaries whose functional currency is a currency other than the U.S. dollar at the applicable foreign exchange rates in effect during the comparable prior-year period and adjusting for the effects of hedging transactions on reported revenue, which are recorded in the U.S. dollar. The constant currency revenue adjustments of ($1.9) million and $ (0.8) million to reported revenue for the three and nine-month periods ended September 30, 2025, respectively, were calculated using the applicable average foreign exchange rates for the three and nine-month periods ended September 30, 2024. Constant Currency Revenue, Organic Merit’s constant currency revenue, organic, is defined, with respect to prior fiscal year periods, as GAAP revenue. With respect to current fiscal year periods, constant currency revenue, organic, is defined as constant currency revenue (as defined above), less revenue from certain acquisitions. For the three-month period ended September 30, 2025, Merit’s constant currency revenue, organic, excludes revenues attributable to products acquired in connection with (i) Merit’s merger transaction with Biolife Delaware, L.L.C. (“Biolife”) in May 2025 (the “Biolife Merger”) and (ii) the assets acquired from Cook Medical Holdings LLC in November 2024 (the “Cook Transaction”). For the nine-month period ended September 30, 2025, Merit’s constant currency revenue, organic, excludes revenues attributable to products acquired in connection with (i) the Biolife Merger, (ii) the Cook Transaction and (iii) the assets acquired from EndoGastric Solutions, Inc. in July 2024. Non-GAAP Gross Profit and Margin Non-GAAP gross profit is calculated by reducing GAAP cost of sales by amounts recorded for amortization of intangible assets and inventory mark-up related to acquisitions. Non-GAAP gross margin is calculated by dividing non-GAAP gross profit by reported net sales. Non-GAAP Operating Income and Margin Non-GAAP operating income is calculated by adjusting GAAP operating income for certain items which are deemed by Merit’s management to be outside of core operations and vary in amount and frequency among periods, such as expenses related to acquisitions or other extraordinary transactions, non-cash expenses related to amortization or write-off of previously acquired tangible and intangible assets, certain employee termination benefits, performance-based stock compensation expenses, expenses resulting from non-ordinary course litigation or administrative proceedings and resulting settlements, governmental proceedings, and changes in governmental or industry regulations, as well as other items referenced in the tables below. Non-GAAP operating margin is calculated by dividing non-GAAP operating income by reported net sales. Non-GAAP Net Income Non-GAAP net income is calculated by adjusting GAAP net income for the items set forth in the definition of non-GAAP operating income above, as well as for expenses related to debt issuance costs, gains or losses on disposal of certain assets, equity method investment loss (income) from equity investees, and other items set forth in the tables below. Non-GAAP EPS Non-GAAP EPS is defined as non-GAAP net income divided by the diluted shares outstanding for the corresponding period. Free Cash Flow Free cash flow is defined as cash flow from operations calculated in accordance with GAAP, less capital expenditures for property and equipment calculated in accordance with GAAP, as set forth in the consolidated statement of cash flows. Other Non-GAAP Financial Measure Reconciliations The following tables set forth supplemental financial data and corresponding reconciliations of non-GAAP financial measures to Merit’s corresponding financial measures prepared in accordance with GAAP, in each case, for the three and nine-month periods ended September 30, 2025 and 2024. The non-GAAP income adjustments referenced in the following tables do not reflect non-performance-based stock compensation expense of $4.6 million and $3.1 million for the three-month periods ended September 30, 2025 and 2024, respectively and $13.9 million and $9.6 million for the nine-month periods ended September 30, 2025 and 2024, respectively. Reconciliation of GAAP Net Income to Non-GAAP Net Income(Unaudited, in thousands except per share amounts)  Three Months Ended September 30, 2025 Pre-Tax Tax Impact After-Tax Per Share ImpactGAAP net income$38,540  $(10,785) $27,755  $0.46             Non-GAAP adjustments:           Cost of Sales           Amortization of intangibles 19,212   (4,539)  14,673   0.24 Inventory mark-up related to acquisitions 183   (43)  140   0.00 Operating Expenses           Contingent consideration expense 32   (5)  27   0.00 Amortization of intangibles 2,560   (604)  1,956   0.03 Performance-based share-based compensation (a) 9,028   (1,413)  7,615   0.13 Corporate restructuring (b) 286   (67)  219   0.00 Acquisition-related (68)  16   (52)  (0.00)Medical Device Regulation expenses (c) 1,655   (391)  1,264   0.02 Other (d) 74   (17)  57   0.00 Other (Income) Expense           Amortization of long-term debt issuance costs 1,414   (334)  1,080   0.02 Other non-operating loss (e) 260   (61)  199   0.00             Non-GAAP net income$73,176  $(18,243) $54,933  $0.92             Diluted shares          59,919   Three Months Ended September 30, 2024 Pre-Tax Tax Impact After-Tax Per Share ImpactGAAP net income$36,657 $(8,213) $28,444 $0.48            Non-GAAP adjustments:           Cost of Sales           Amortization of intangibles 14,896  (3,522)  11,374  0.19Inventory mark-up related to acquisitions 559  (132)  427  0.01Operating Expenses           Contingent consideration expense 103  (6)  97  0.00Amortization of intangibles 2,038  (482)  1,556  0.03Performance-based share-based compensation (a) 3,736  (609)  3,127  0.05Corporate restructuring (b) 2,084  (492)  1,592  0.03Acquisition-related 2,351  (555)  1,796  0.03Medical Device Regulation expenses (c) 1,983  (468)  1,515  0.03Other (d) 125  (30)  95  0.00Other (Income) Expense           Amortization of long-term debt issuance costs 1,477  (349)  1,128  0.02            Non-GAAP net income$66,009 $(14,858) $51,151 $0.86            Diluted shares          59,537 ___________________ Note: Certain per-share impacts may not sum to totals due to rounding. Reconciliation of GAAP Net Income to Non-GAAP Net Income(Unaudited, in thousands except per share amounts)  Nine Months Ended September 30, 2025 Pre-Tax Tax Impact After-Tax Per Share ImpactGAAP net income$119,877 $(29,394) $90,483  $1.49             Non-GAAP adjustments:           Cost of Sales           Amortization of intangibles 55,798  (13,184)  42,614   0.70 Inventory mark-up related to acquisitions 250  (59)  191   0.00 Operating Expenses           Contingent consideration expense 1,198  29   1,227   0.02 Amortization of intangibles 7,497  (1,771)  5,726   0.09 Performance-based share-based compensation (a) 19,681  (2,344)  17,337   0.29 Corporate restructuring (b) 2,873  (678)  2,195   0.04 Acquisition-related 2,088  (2)  2,086   0.03 Medical Device Regulation expenses (c) 4,883  (1,153)  3,730   0.06 Other (d) 103  (24)  79   0.00 Other (Income) Expense           Amortization of long-term debt issuance costs 4,242  (1,002)  3,240   0.05 Other non-operating loss (gain) (e) 11  (61)  (50)  (0.00)            Non-GAAP net income$218,501 $(49,643) $168,858  $2.79             Diluted shares          60,604   Nine Months Ended September 30, 2024 Pre-Tax Tax Impact After-Tax Per Share ImpactGAAP net income$116,848 $(24,438) $92,410 $1.57            Non-GAAP adjustments:           Cost of Sales           Amortization of intangibles 40,827  (9,654)  31,173  0.53Inventory mark-up related to acquisitions 559  (132)  427  0.01Operating Expenses           Contingent consideration expense 292  (31)  261  0.00Amortization of intangibles 5,546  (1,312)  4,234  0.07Performance-based share-based compensation (a) 9,396  (1,466)  7,930  0.13Corporate restructuring (b) 2,030  (479)  1,551  0.03Acquisition-related 3,610  (852)  2,758  0.05Medical Device Regulation expenses (c) 6,120  (1,445)  4,675  0.08Other (d) 302  (72)  230  0.00Other (Income) Expense           Amortization of long-term debt issuance costs 4,431  (1,046)  3,385  0.06            Non-GAAP net income$189,961 $(40,927) $149,034 $2.53            Diluted shares          58,948 ___________________ Note: Certain per-share impacts may not sum to totals due to rounding. Reconciliation of Reported Operating Income to Non-GAAP Operating Income(Unaudited, in thousands except percentages)  Three Months Ended Three Months Ended Nine Months Ended Nine Months Ended September 30, 2025 September 30, 2024 September 30, 2025 September 30, 2024 Amounts % Sales Amounts % Sales Amounts % Sales Amounts % SalesNet Sales as Reported$384,157     $339,845    $1,121,970    $1,001,356                           GAAP Operating Income 42,612  11.1 %  37,261 11.0%  130,525 11.6%  119,129 11.9%Cost of Sales                       Amortization of intangibles 19,212  5.0 %  14,896 4.4%  55,798 5.0%  40,827 4.1%Inventory mark-up related to acquisitions 183  0.0 %  559 0.2%  250 0.0%  559 0.1%Operating Expenses                       Contingent consideration expense 32  0.0 %  103 0.0%  1,198 0.1%  292 0.0%Amortization of intangibles 2,560  0.7 %  2,038 0.6%  7,497 0.7%  5,546 0.6%Performance-based share-based compensation (a) 9,028  2.4 %  3,736 1.1%  19,681 1.8%  9,396 0.9%Corporate restructuring (b) 286  0.1 %  2,084 0.6%  2,873 0.3%  2,030 0.2%Acquisition-related (68) (0.0)%  2,351 0.7%  2,088 0.2%  3,610 0.4%Medical Device Regulation expenses (c) 1,655  0.4 %  1,983 0.6%  4,883 0.4%  6,120 0.6%Other (d) 74  0.0 %  125 0.0%  103 0.0%  302 0.0%                        Non-GAAP Operating Income$75,574  19.7 % $65,136 19.2% $224,896 20.0% $187,811 18.8% ___________________ Note: Certain percentages may not sum to totals due to rounding. (a)Represents performance-based share-based compensation expense, including stock-settled and cash-settled awards.(b)Includes employee termination benefits associated with activities related to corporate restructuring initiatives and costs to terminate certain distribution contracts from our Biolife Merger.(c)Represents incremental expenses incurred to comply with the E.U. Medical Device Regulation.(d)Represents costs to comply with Merit’s corporate integrity agreement with the U.S. Department of Justice (the “DOJ”).(e)Includes gains and losses associated with the disposal of business units and equity method investment loss (income) from equity investees. Reconciliation of Reported Revenue to Constant Currency Revenue (Non-GAAP), and Constant Currency Revenue, Organic (Non-GAAP)(Unaudited, in thousands except percentages)    Three Months Ended   Nine Months Ended   September30,    September30,  % Change 2025 2024 % Change 2025 2024Reported Revenue13.0%$384,157  $339,845 12.0%$1,121,970  $1,001,356                Add: Impact of foreign exchange   (1,926)  —    (778)  —                Constant Currency Revenue (a)12.5%$382,231  $339,845 12.0%$1,121,192  $1,001,356                Less: Revenue from certain acquisitions   (16,031)  —    (51,445)  —                Constant Currency Revenue, Organic (a)7.8%$366,200  $339,845 6.8%$1,069,747  $1,001,356 ___________________ (a)A non-GAAP financial measure. For a definition of this and other non-GAAP financial measures, see the section of this release entitled “Non-GAAP Financial Measures.” Reconciliation of Reported Gross Margin to Non-GAAP Gross Margin (Non-GAAP)(Unaudited, as a percentage of reported revenue)  Three Months Ended Nine Months Ended September30,  September30,  2025 2024 2025 2024Reported Gross Margin48.5% 46.4% 48.4% 47.0%            Add back impact of:           Amortization of intangibles5.0% 4.4% 5.0% 4.1%Inventory mark-up related to acquisitions0.0% 0.2% 0.0% 0.1%            Non-GAAP Gross Margin53.6% 50.9% 53.4% 51.1% ___________________ Note: Certain percentages may not sum to totals due to rounding. ABOUT MERIT Founded in 1987, Merit is engaged in the development, manufacture, and distribution of proprietary medical devices used in interventional, diagnostic, and therapeutic procedures, particularly in cardiology, radiology, oncology, critical care, and endoscopy. Merit serves customers worldwide with a domestic and international sales force and clinical support team totaling more than 800 individuals. Merit employs approximately 7,400 people worldwide. CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING STATEMENTS This release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements include, among others: statements preceded or followed by, or that include the words, “may,” “will,” “should,” “expects,” “plans,” “anticipates,” “intends,” “seeks,” “believes,” “estimates,” “projects,” “forecasts,” “potential,” “target,” “continue,” “upcoming,” “optimistic” or other forms of these words or similar words or expressions, or the negative thereof or other comparable terminology;statements that address Merit’s future operating performance or events or developments that Merit’s management expects or anticipates will occur, including, without limitation, any statements regarding Merit’s projected revenues, earnings or other financial measures, Merit’s plans and objectives for future operations, Merit’s proposed new products or services, the integration, development or commercialization of the business or any assets acquired from other parties, future economic conditions or performance, the implementation of, and results which may be achieved through, Merit’s Continued Growth Initiatives Program or other business optimization initiatives, and any statements of assumptions underlying any of the foregoing; andstatements regarding Merit’s past performance, efforts, or results about which inferences or assumptions may be made, including statements proceeded or followed by the words “preliminary,” “initial,” “potential,” “possible,” “diligence,” “industry-leading,” “compliant,” “indications,” or “early feedback” or other forms of these words or similar words or expressions, or the negative thereof or other comparable terminology. The forward-looking statements contained in this release are based on Merit management’s current expectations and assumptions regarding future events or outcomes. If underlying expectations or assumptions prove inaccurate, or risks or uncertainties materialize, actual results will likely differ, and could differ materially, from Merit’s expectations reflected in any forward-looking statements. Financial estimates are subject to change and are not intended to be relied upon as predictions of future operating results. Investors are cautioned not to unduly rely on any such forward-looking statements. The following are some of the important risks and uncertainties that could cause Merit’s actual results to differ from management’s expectations in any forward-looking statements: risks and uncertainties associated with consequences of Merit’s executive succession planning activities and leadership transition; risks and uncertainties regarding trade policies or related actions implemented by the U.S. or other countries, including existing, proposed or prospective tariffs, duties or other measures; risks and uncertainties associated with Merit’s proposed acquisition of the C2 CryoBalloon device and related assets from Pentax of America, Inc., the possibility that Merit may not complete the proposed acquisition and, if the acquisition is completed, Merit’s integration of the acquired products and Merit’s ability to achieve projected financial results, product development and other projected benefits of the proposed acquisition; risks and uncertainties associated with Merit’s integration of the Biolife business and operations and its ability to achieve financial results, product development and other anticipated benefits of such acquisition; risks and uncertainties associated with Merit’s integration of products acquired in the Cook Transaction and Merit’s ability to achieve anticipated financial results, product development and other anticipated benefits of such acquisition; effects of the Convertible Notes on Merit’s net income and earnings per share performance; disruptions in Merit’s supply chain, manufacturing or sterilization processes; U.S. and global political, economic, competitive, reimbursement and regulatory conditions, including the ongoing “shutdown” of the United States government; modification or limitation of, or policies and procedures associated with, governmental or private insurance reimbursement policies; reduced availability of, and price increases associated with, components and other raw materials; increases in transportation expenses; risks relating to Merit’s potential inability to successfully manage growth through acquisitions generally, including the inability to effectively integrate acquired operations or products or commercialize technology developed internally or acquired through completed, proposed or future transactions; fluctuations in interest or foreign currency exchange rates and inflation; cybersecurity events; government scrutiny and regulation of the medical device industry; difficulties relating to development, testing and regulatory approval, clearance and maintenance of Merit’s products; the safety, efficacy and patient and physician adoption of Merit’s products; the ability to fully enroll and the outcomes of ongoing and future clinical trials and market studies relating to Merit’s products; litigation and other judicial proceedings affecting Merit; consequences associated with a Corporate Integrity Agreement executed between Merit and the U.S. Department of Justice; failure to comply with U.S. and foreign laws and regulations; restrictions on Merit’s liquidity or business operations resulting from its debt agreements; infringement of Merit’s technology or the assertion that Merit’s technology infringes the rights of other parties; product recalls and product liability claims; potential for significant adverse changes in governing regulations; changes in tax laws and regulations in the United States or other jurisdictions or exposure to additional tax liabilities which may adversely affect Merit’s effective tax rate; termination of relationships with Merit’s suppliers, or failure of such suppliers to perform; development of new products and technology that could render Merit’s existing or future products obsolete; market acceptance of new products; failure to comply with applicable environmental laws; changes in key personnel; labor shortages and increases in labor costs; price and product competition; extreme weather events; and geopolitical events. For a further discussion of the risks and uncertainties which may affect Merit’s business, operations and financial condition, see Part I, Item 1A. “Risk Factors” in Merit’s Annual Report on Form 10-K for the year ended December 31, 2024 filed with the SEC, which Merit updated in Part II, Item 1A. “Risk Factors” in Merit’s Quarterly Reports on Form 10-Q for each of the quarters ended March 31, 2025, June 30, 2025 and September 30, 2025, which Merit filed with the SEC. All subsequent forward-looking statements attributable to Merit or persons acting on its behalf are expressly qualified in their entirety by these cautionary statements. Actual results will likely differ, and may differ materially, from anticipated results. Financial estimates are subject to change and are not intended to be relied upon as predictions of future operating results. Those estimates and all other forward-looking statements included in this release are made only as of the date of this release, and except as otherwise required by applicable law, Merit assumes no obligation to update or disclose revisions to estimates and all other forward-looking statements. TRADEMARKS Unless noted otherwise, trademarks and registered trademarks used in this release are the property of Merit Medical Systems, Inc., its subsidiaries, or its licensors. Contacts: PR/Media Inquiries:Sarah Comstock Merit MedicalInvestor Inquiries:Mike Piccinino, CFA, IRCICR Healthcare+1-801-432-2864+1-443-213-0509sarah.comstock@merit.commike.piccinino@icrhealthcare.com

BridgeBio Reports Third Quarter 2025 Financial Results and Business Updates

-$120.7 million in total third quarter revenue, comprised of $108.1 million of U.S. Attruby® net product revenue, $4.3 million from royalty revenue, and $8.3 million in license and services revenue  -As of October 25, 2025, 5,259 unique patient prescriptions have been written by 1,355 unique prescribers, representing an accelerating launch driven by strong month over month growth in the crucial treatment naïve patient segment  -Attruby continues to differentiate clinically by proving its unique profile in new subpopulations and holistic analyses:  -JACC publication demonstrated the effect of Attruby on cumulative cardiovascular outcomes within the first month of treatment    -Positive topline interim analysis results from FORTIFY, the registrational Phase 3 study of BBP-418, a small molecule in development for LGMD2I/R9  -Primary interim analysis endpoint, glycosylated αDG, significantly increased by 1.8x change from baseline at 3 months (p